| 丹参中丹参素、原儿茶醛来源的初步研究 |
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| 引用本文： | 徐德然,王康才,王峥涛,王长江,胡军.丹参中丹参素、原儿茶醛来源的初步研究[J].中国天然药物,2005,3(3):148-150. |
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| 作者姓名： | 徐德然 王康才 王峥涛 王长江 胡军 |
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| 作者单位： | 1. 中国药科大学中药学院,南京,210038
2. 南京农业大学园艺学院,南京,210095 |
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| 摘 要： | 目的：考察丹参药材中丹参素和原儿茶醛的来源。方法：以丹参素、原儿茶醛为指标成分，用高效液相色谱法测定其含量；采用液相色谱与多级质谱联用法鉴定丹酚酸。结果：丹参素、原儿茶醛并非丹参固有成分，随煎煮时间增加而增加，而丹酚酸B随煎煮时间增加而减少。结论：丹参素、原儿茶醛是丹酚酸B的降解产物。
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| 关 键 词： | 原儿茶醛 丹参素 步研究 高效液相色谱法 煎煮时间 丹酚酸B 指标成分 降解产物 联用法 |
| 文章编号： | 1672-3651(2005)03-0148-03 |
| 修稿时间： | 2004年6月21日 |
Primary Study on the Original Problems of Danshensu and Protocatechuic Aldehyde of Salvia miltiorrhiza |
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| XU De-ran,WANG Kang-Cai,WANG Zheng-Tao,WANG Chang-jiang,HU Jun.Primary Study on the Original Problems of Danshensu and Protocatechuic Aldehyde of Salvia miltiorrhiza[J].Chinese JOurnal of Natural Medicines,2005,3(3):148-150. |
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| Authors: | XU De-ran WANG Kang-Cai WANG Zheng-Tao WANG Chang-jiang HU Jun |
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| Abstract: | AIM:To see about the original problems of the water-soluble compounds(danshensu and protocatechuic aldehyde)in Danshen,as well as the methodological study of the extraction methods.METHOD:Several extraction methods for Radix Salvia miltiorrhiza (ultrasonic extraction and decoction)were compared. The extraction yields of danshensu and protocatechuic aldehyde were determined quantitatively by HPLC.Three Salvianolic acids were identified by LC/MS~(n) technique.RESULT:Danshensu and protocatechuic aldehyde are not the original compounds of Radix Salviae miltiorrhizae.And the yield of salvianolic acid B decreased with the time of decoction passing by.CONCLUSION:They are possibly the degraded artifacts of salvianolic acid B. |
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| Keywords: | Salvia miltiorrhiza Bge Danshensu Protocatechuic aldehyde LC/MS~(n) |
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