运脾止泻颗粒治疗小儿腹泻的临床疗效观察

目的观察运脾止泻颗粒治疗小儿腹泻病的临床疗效。方法随机选择300例患儿分为两组进行临床观察，即治疗组150例口服中药运脾止泻颗粒、对照组150例口服西药思密达，两组疗程均为7天：观察两组疗效，检测粪常规、粪培养、粪轮状病毒抗原及尿D-木糖含量。结果临床研究结果显示：治疗组迁延性腹泻、脾虚型腹泻有效率均优于对照组（P〈0．05），粪常规转阴、好转率优于对照组（P〈0．05）；而粪培养转阴率、粪轮状病毒抗原转阴率、尿D-木糖含量测定前后比较，差异无显著性（P〉0．05）。结论运脾止泻颗粒能有效治疗小儿腹泻病，尤其对迁延性腹泻、脾虚型腹泻疗效满意。

Clinical Research on Effects of Yunpi Zhixie Granule in Children with Diarrhea

Objective To investigate the clinical effect of Yunpi Zhixie Granule(YZG)on children's diarrhea.Methods Three hundred diarrhea cases were randomly divided into two groups equally,the treated group treated by YZG orally and the control group by smacta,both for 7 days.The clinical efficacy was observed,routine scatologic analysis,scatologic cultivation,rotavirus antigen and urinary D-xylose content were detected.Results Clinical results showed the effective rate in treating the chronic or Pi-deficiency diarrhea as well as the negative conversion rate and improvement rate of routine scatologic analysis were all higher in the treated group than those in the control group(P<0.05);while no significant difference was found in negative conversion rate of scatologic cultivation and rotavirus antigen and urinary D-xylose content after treatment,compared with those before treatment(P>0.05).Conclusion WT5BZ]YZG was effective in treating children's diarrhea,especially on chronic diarrhea and diarrhea of Pi-deficiency type.