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生血合剂治疗再生障碍性贫血的临床研究
引用本文:周永明,黄振翘,黄韬,薛志忠,周韶虹,陆嘉惠,李艳红.生血合剂治疗再生障碍性贫血的临床研究[J].中国中西医结合杂志,2000,20(3):173-175.
作者姓名:周永明  黄振翘  黄韬  薛志忠  周韶虹  陆嘉惠  李艳红
作者单位:上海中医药大学附属岳阳医院
摘    要:目的:观察生血合剂治疗再生障碍性贫血(简称再障)的临床疗效,探讨可能的疗效机理。方法:治疗组84例,脾肾阳虚型用生血Ⅰ号合剂,脾肾阴虚型用生血Ⅱ号合剂治疗;对照组30例用康力龙治疗,观察临床疗效和多项实验指标的变化。结果:治疗组基本治愈率,缓解率,总有效率分别为21.43%,27.38%,86.90%,对照组依次为3.33%,20.00%,56.67%,两组总胶前性差异,治疗组疗效明显优于对照组,

关 键 词:再生障碍性贫血  中医药疗法  生血合剂  临床研究

Clinical Study of Shengxue Mixture in Treating Aplastic Anemia
Authors:ZHOU Yongming  HUANG Zhenqiao  HUANG Tao  Affiliated Yueyang Hospital  Shanghai University of TCM  Shanghai
Institution:Affiliated Yueyang Hospital, Shanghai University of TCM, Shanghai (200437).
Abstract:To observe the clinical effect of Shengxue mixture (SXM) in treating aplastic anemia, and studied its mechanism. Methods: Eighty-four patients of the treated group, those with Spleen-Kidney Yang deficiency Syndrome and Spleen-Kidney Yin deficiency Syndrone were treated with SXM-A and SXM-B respectively, and 30 patients of the control group were treated with Stanozolol. The clinical effect and several experimental parameters were also observed. Results: The basic cure rate, remission rate, total effective rate of the treated and control group were 21. 43%, 27.38%, 86.90% and 3.33%, 20.00%, 56.67% respectively, the difference between 2 groups was significant (P<0.05, P<0.01). The effect of the treated group was obviously better than that of the control group. While the patients' symptoms were alleviated, the peripheral blood cells increased, the ratio of T lymphocyte subsets tended to balance, the level of natural killer cells activity increased, interleukin 2 reduced, and the reproduction of the bone marrow were markedly improved in most of the patients treated by SXM. Conclusion: SXM is an effective and safe drug for aplastic anemia. Its mechanism might be regulating the immune function, which facilitated the recovery of the bone marrow hematopoiesis function.
Keywords:Shengxue mixture  aplastic anemia  clinical study
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