T细胞亚群测定与卵巢肿瘤辨证分型关系的研究

本研究应用流式细胞仪和单克隆抗体技术测定了７３例卵巢肿瘤患者外周血Ｔ淋巴细胞亚群，试图阐明卵巢肿瘤患各证型之间的免疫状况。结果显示：卵巢肿瘤患者外周血Ｔ细胞亚群变化与辨证分型有关，可作为临床判断虚证，实证及其免疫状况的敏感指标，为中医治疗卵巢提供了客观依据。

Relationship between T Cell Subsets and TCM Type in Ovarian Tumor Patients

In order to study the difference in TCM types as well as between Deficiency and Excess type in immunity in the patients with ovarian tumors,the profile of peripheral blood T lymphocyte subsets in 73 cases of ovarian tumors was determined by using flow cytometry and monoclonal antibody technique. The results showed that the total T cells (OKT3) of peripheral blood were almost normal in 73 tumor cases. And 50 of them were malignant tumors in which T helper cell were progressively decreased and T suppresser cell gradually increased in accordance with the order of Qi-Deficiency,Yin-Deficiency, Qi-Yin Deficiency types. The T4/T8 ratio showed significant difference (P<0.01)compared with the control group and the initial ovarian tumor group. These results indicated that the change in the T lymphocyte subset in tumor was correlated with TCM type and this serves as both clinically sensitive indexes of different TCM type and reflection of the patient's immunologic status.