中孚降压胶囊治疗高血压病阴虚阳亢证临床观察 |
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引用本文: | 寇秋爱,于华萍,周国栋,柏燕君,涂秀华.中孚降压胶囊治疗高血压病阴虚阳亢证临床观察[J].中国中西医结合杂志,2007,27(8):745-748. |
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作者姓名: | 寇秋爱 于华萍 周国栋 柏燕君 涂秀华 |
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作者单位: | 1. 中国中医科学院西苑医院,北京,100091 2. 北京市门头沟区中医院 |
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摘 要: | 目的 观察中孚降压胶囊治疗高血压病(阴虚阳亢证)的临床疗效及安全性.方法 采用分层区组随机、双盲双模拟、阳性药平行对照、多中心临床试验的方法.试验组口服中孚降压胶囊(0.5 g/粒,每次3粒,每天2次)及洛丁新片模拟剂(10 mg/片,每次1片,每天1次);对照组口服洛丁新片(10 mg/片,每次1片,每天1次)及中孚降压胶囊模拟剂(0.5 g/粒,每次3粒,每天2次),4周为1个疗程,观察两组的降压效果及中医证候疗效.结果 试验组降压显效率58.65%,总有效率79.81%;对照组分别为60.51%,78.34%;试验组中医证候显效率21.15%,总有效率78.85%;对照组为分别25.48%、86.62%,两组降压效果及中医证候比较,总有效率、显效率差异均无显著性(P>0.05).结论 中孚降压胶囊治疗高血压病疗效明显而且安全性良好.
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关 键 词: | 中孚降压胶囊 洛丁新片 高血压病 阴虚阳亢证 |
收稿时间: | 2006-10-23 |
修稿时间: | 2007-05-08 |
Clinical Observation on Treatment of Hypertension (Yin-Deficiency with Sthenic-Yang Syndrome Type) with Zhongfu Hypotension Capsule |
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Authors: | KOU Qiu-ai YU Hua-ping ZHOU Guo-dong |
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Abstract: | Objective To observe the efficacy and safety of Zhongfu Hypotension Capsule (ZHC) in treating hypertension of yin-deficiency with sthenic-yang syndrome type. Methods Adopting the stratified, block randomized, double-blinded, double-dummy, positive parallel controlled, multi-centered clinical trial method, the tested group was treated by orally taken 3 capsules of ZHC (0.5 g/capsule) twice a day, and the control group was treated by orally taken Lotensin Tablet 1 tablet (10 mg/tab.) once a day. And all received the adiaphorous drug with the dosage-form mimic to that used in the tested group. The therapeutic course was 4 weeks for both groups. Results The markedly effective rate and the total effective rate in reducing blood pressure was 58.65% and 79.81% respectively in the tested group,and 60.51% and 78.34% respectively in the control group; while the markedly effective rate and the total effective rate for alleviating TCM syndrome was 21.15% and 78.85% in the tested group, and 25.48% and 86.62% in the control group respectively. Comparisons between the two groups showed insignificant difference (P>0.05) .Conclusion ZHC has good efficacy and is safety in treating hypertension. |
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Keywords: | Zhongfu Hypotension Capsule Lotensin Tablet hypertension yin-deficiency with sthenic-yang syndrome |
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