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康胃颗粒治疗慢性萎缩性胃炎胃癌前期病变的疗效观察
引用本文:吴耀南,陈一斌,王文凡,涂志红.康胃颗粒治疗慢性萎缩性胃炎胃癌前期病变的疗效观察[J].中国中西医结合杂志,2005,25(9):836-839.
作者姓名:吴耀南  陈一斌  王文凡  涂志红
作者单位:厦门市中医院,福建,361001
摘    要:目的 观察康胃颗粒治疗慢性萎缩性胃炎(CAG)胃癌前期病变(GPL)中医辨证属脾虚湿热血瘀证患者的疗效。方法 选择确诊为GPL,中医辨证属脾虚湿热血瘀证患者68例,随机分为两组,治疗组36例予康胃颗粒治疗,对照组32例子胃复春治疗,12周为1个疗程,均治疗2个疗程。结果 治疗组的胃镜疗效和病理疗效均显著优于对照组(P〈0.05);两组患者的临床疗效、症状疗效和抗HP疗效的比较,差异均无显著性(P〉0.05)。结论 康胃颗粒是一种治疗GPL的有效药物。

关 键 词:慢性萎缩性胃炎  胃癌前期病变  脾虚湿热血瘀证  康胃颗粒  疗效观察  治疗组  颗粒  脾虚湿热  中医辨证  临床疗效
收稿时间:2005-03-25
修稿时间:2005-06-28

Clinical Study on Effects of Kangwei Granule on Precancerous Lesion in Patients with Chronic Atrophic Gastritis
Authors:WU Yao-nan  CHEN Yi-bin  WANG Wen-fan
Institution:Xiamen Hospital of TCM, Fujian 361001
Abstract:ObjectiveTo study the effects of Kangwei Granule (KWG) on gastric precancerous lesion (GPL) in patients suffered from chronic atrophic gastritis (CAG) differentiated as Pi-deficiency with damp-heat retention and blood stasis in TCM Syndrome differentiation. MethodsSixty-eight patients fitting to the admittion criteria were randomly divided into two groups, 36 patients were treated with KWG in the treated group and 32 were treated with Weifuchun in the control group, all were treated for 2 treatment courses (12 weeks as one course). ResultsThe curative effects on gastroscopy and pathologic changes in the treated group were significantly superior to those in the control group (P<0.05). The comparison of clinical efficacy, symptom improvement, anti-Helicobactor pylori effect between the two groups was insignificantly different (P>0.05). ConclusionKWG is an effective drug for GPL.
Keywords:chronic atrophic gastritis  gastric precancerous lesion  Pi-deficiency Syndrome with damp-heat retention and blood stasis  Kangwei Granule
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