参麦注射液对充血性心力衰竭的疗效观察

目的：观察参麦注射液对充血性心力衰竭患者的临床疗效。方法：应用随机交叉对比的方法，对１６例慢性充血性心力衰竭进行参麦注射液和门冬氨酶钾镁治疗比较。结果：应用参麦注射液２周后，左室射血分数由２９．５±９．０升至３６．６±１０．２，６８．７５％的患者心功能改善，未发现明显毒副作用；阂冬氨酸钾镁可使３７．５０％的患者心功能改善，但左室身因分数无明显变化。结论：参麦注射液是治疗充血性心力竭的有效药物。

Observation on Effect of Shenmai Injection in Treating Patients of Congestive Heart Failure

OBJECTIVE: To observe the clinical therapeutic effect of Shenmai Injection (SMI) in treating patients of congestive heart failure. METHODS: Effect of 16 cases treated with SMI or potassium magnesium aspartate was observed by randomized crossover method and compared. RESULTS: By using SMI for 2 weeks, patients' left ventricular ejective fraction (LVEF) could be increased from 29.5 +/- 9.0 to 36.6 +/- 10.2 (P < 0.05), the heart function of 68.75% patients was improved, no side effects or toxicity was observed. Potassium magnesium asparate could improve heart function in 37.50% patients only but with no effect on LVEF. CONCLUSION: SMI is an effective and safe therapy in treating patients with congestive heart failure.