| 三才注射液对小鼠红系细胞的影响 |
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| 引用本文： | 王来慈,张志华,钱金钰,李忠立,齐笑庸.三才注射液对小鼠红系细胞的影响[J].中国中西医结合杂志,1998,18(3):165-167. |
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| 作者姓名： | 王来慈 张志华 钱金钰 李忠立 齐笑庸 |
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| 作者单位： | 哈尔滨医科大学附属第二医院血液病研究所!哈尔滨150086(王来慈，张志华，钱金钰，李忠立)，哈尔滨医科大学附属第二医院血液病研究所!哈尔滨15(齐笑庸) |
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| 基金项目： | 黑龙江省科学技术委员会资助课题!(No.G92C
2 40 80 5 0 2 ) |
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| 摘 要： | 目的：探讨三才封髓丹对小鼠红系细胞造血的作用机理。方法：通过应用三才注射液对贫血及正常小鼠外周血的Ｈｂ、ＲＢＣ、网织红细胞（Ｒｅｔ）、红系分裂指数、骨髓有核细胞（ＢＭＣ）进行测定及采用红系造血祖细胞的培养方法，观察三才封髓丹的造血作用。结果：三才封髓丹能促进贫血小鼠的Ｈｂ、ＲＢＣ、Ｒｅｔ、红系分裂指数、ＢＭＣ的增加，在脾细胞或腹腔巨噬细胞条件下，能促进ＢＦＵ－Ｅ及ＣＦＵ－Ｅ的增殖。结论：三才封髓丹
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| 关 键 词： | 三才封髓丹 红系造血祖细胞 脾细胞 巨噬细胞 |
Effect of Sancai Injection on Red Blood Cell Line in Mice |
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| Authors: | Wang Laici Zhang Zhihua Qian Jinyu The Se cond Affiliated Hospilal Harbin Medical University Harbin |
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| Abstract: | Objective: To study the effective mechanism of Sancai Fensui Dan in mice.Methods: Sancai injection (SCI) was given to normal or anemia mice and their hemoglobin (Hb), red blood cell (RBC), reticulocyte (Ret) of peripheral blood, mitosis index (MI) of red cells, bone marrow nucleated cell (BMC) were measured. And the cultured hemopoietic progenitor cells of burst forming unit erythroid (BFU E) and colony forming unit erythroid (CFU E) were used to observe the hemopoiesis effect of SCI. Results: SCI could promote the increase of Hb, RBC, Ret, MI and BMC in anemia mice. At the presence of spleen cells or macrophages in peritoneal cavity, it could enhance the proliferation of BFU E and CFU E.Conclusion: SCI could promote hemopoiesis by activating the hemo opsonin. |
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| Keywords: | Sancai Fengsui Dan hemopoietic progenitor cell of red blood cell line spleen cell macrophage |
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