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舒心饮改善冠心病左心室舒张功能障碍的临床研究
引用本文:陈伟,何燕,林钟香,肖沪生,陈长勋.舒心饮改善冠心病左心室舒张功能障碍的临床研究[J].中国中西医结合杂志,1995,15(5):271-273.
作者姓名:陈伟  何燕  林钟香  肖沪生  陈长勋
作者单位:上海中医药大学附属龙华医院
摘    要:我们应用多普勒超声心动图检查了31例冠心病左心室舒张功能不全患者在舒心饮治疗前后舒张功能的变化以及临床症状,体征,心电图和血脂的变化。经过1个月的治疗后,患者的症状,征及心电图较治疗前好转,临床症状有效率为87.1%,血脂下降(P〈0.05)。多普勒超声心动图的主要变化为,E波峰值由44.8±10.8cm.s^-^1提高到57.1±11.0cm.s^-^1(P〈0.01),E波面积由26.3±6。

关 键 词:左室舒张功能  超声心动图  舒心饮  冠心病

Clinical Study of Improving Effect of Shuxinyin on Abnormal Left Ventricular Diastolic Function in Coronary Heart Disease
Authors:Chen Wei  He Yan  Lin Zhong-xiang
Abstract:There was evidence that abnormal left ventricular diastolic function was common in patients with coronary heart disease which led to symptoms such as dyspnea on exertion,distress in chest etc,even overt congestive heart failure.The changes of left ventricular diastolic function were examined with pulsed doppler echocardiography as well as of clinical symptoms,signs,electrocardiographic findings and plasma lipoprotein after Shuxinyin(SXY) therapy in 31 patients with coronary heart disease and abnormal left ventricular diastolic function.The SXY mainly consists of medicinal herbs capable of tonifying Qi and Yin. After treatment for one month the symptoms, signs and ECG were improved, the symptomatic effective rate was 87.1%.Plasma lipoprotein was reduced(P<0.05).The main changes in doppler echocardiography were as follows.The peak of E wave, the area of E wave and Dec rate increased significantly(P<0.01).The ratio of A wave peak to E wave peak was decreased. The changes in peak of A wave, the area of A wave and time index were insignificant(P>0.05). It was concluded that SXY mainly improved the early left ventricular diastolic functions, increased the peak velocity and volume of rapid left ventricular filling blood flow during the early diastole, and thus alleviated symptoms as well as ECG findings.
Keywords:left ventricular diastolic function  doppler echocardiography  tonifying Qi and Yin  Shuxinyin  coronary heart disease  
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