补肾中药密骨片预防老年男性骨质丢失的临床研究

目的：研究补肾中药密骨片预防老年男性骨质疏松的作用。方法：将44例老年男性受试者随机分为中药组和对照组。中药组服用补肾中药密骨片和钙剂，对照组只服用钙剂，均用药1年。研究开始和结束时检测受试者腰椎和股骨上端骨密度，以及血清骨钙素（s-BGP)和尿羟脯氨酸与肌酐比值（Hyp/Cr0。结果：均用药1年后，中药组腰椎骨密度略有上升（P＞0．05），而股骨颈，Ward's三角区和股骨粗隆骨密度则显著上升（P＜0．05；对照组各处骨密度明显下降（P＜0．05）。对照组s-BGP和Hyp/Cr比值均上升（P＜0．05），而中药组则无显著变化。结论：补肾中药密骨片可通过抑制骨转移而防止老年男性骨质丢失。

Clinical Study on Bone Loss Preventive Effect of Chinese Drugs for Tonifying-Shen in Aged Males

Objective: To study the myocardial protective effect of Shengfu Jnjection (SFI) in patients who were undergoing open heart operation. Methods: Thirty eight patients with valvular heart diseases were randomly divided into the control and the tested group. To the patients in the control group, cold crystal hyperpotassium cardio arresting liquid was infused through ascending aorta at initial time, after blood flow being blocked for 20 min, the blood contained cardio arresting liquid was infused every 30 min. To the patients in the tested group, SFI 20 ml/L was also infused in combining with the blood containing cardio arresting liquid at the same time additionally. The two groups were treated in the same way in other aspects. Influence of SFI on myocardial enzyme spectrum (CK MB, LDHI 1) was observed. Results: The changes of myocardial enzyme spectrum in the two groups were not different significantly before operation. They increased obviously after opening the ascending aorta, but the level of increasing in the tested group was much lower than that in the control group, with statistical significance. Conclusion: Myocardial protection may be reached during open heart operation by adding SFI into the blood containing cardio arresting liquid, which could reduce the releasing of myocardial enzyme, so, the mixed liquid shows a myocardial protection effect superior to the simple one.