| 四君子汤对脾虚患者血清可溶性细胞粘附分子—1水平和单核细 … |
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| 引用本文： | 章梅,孙凯.四君子汤对脾虚患者血清可溶性细胞粘附分子—1水平和单核细 …[J].中国中西医结合杂志,1999,19(5):270-272. |
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| 作者姓名： | 章梅 孙凯 |
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| 作者单位： | 第四军医大学西京医院中医科 |
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| 摘 要： | 目的：观察四君子汤对脾虚患者血清可溶性细胞粘附分子－１（ｓＩＣＡＭ－１）和单核细胞功能的影响。方法：采用酶联免疫吸附法和改良噻唑蓝法对６６例脾虚患者血清ｓＩＣＡＭ－１和白细胞介素－１５（ＩＬ－１５）及单核细胞缺本依赖性细胞介导的细胞毒反应（ＡＤＣＣ）进行检测。结果：脾虚患者血清ｓＩＣＡＭ－１水平升高ＩＬ－１５分泌减少，ＡＤＣＣ功能下降，表现为免疫功能低下，经过四君子汤治疗后，上述指标恢复正常。结论
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| 关 键 词： | 脾虚 四君子汤 sICAM－1 IL－15 ADCC |
Effect of Sijunzi Decoction on Serum Soluble Intercellular Adhesive Molecule 1, Interleukin 15 and Monocyte Antibody Dependent Cell Mediated Cytotoxicity in Patients of Spleen Deficiency |
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| Authors: | Zhang Mei Zhang Zhonghai Xia Tian |
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| Abstract: | Objective: To study the effect of Sijunzi Decoction (SJZD) on serum soluble intercellular adhesive molecule 1 (sICAM 1), interleukin 15 (IL 15) and monocyte antibody dependent cell mediated cytotoxicity (ADCC) in patients of Spleen Deficiency. Methods: Serum sICAM 1, IL 15 and monocyte ADCC of 66 Spleen Deficiency patients were determined by enzyme linked immunosorbent assay and modified thiazole blue test. Results: Serum sICAM 1 of Spleen Deficiency patients increased, IL 15 secretion decreased and monocyte ADCC function reduced, which displayed as lowered immune function. After SJZD treatment, all the above mentioned parameters were normalized. Conclusion: SJZD could enhance immune function of organism by strengthening Spleen and tonifying Qi. |
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| Keywords: | patient of Spleen Deficiency Sijunzi Decoction soluble intercellular adhesive molecule 1 interleukin 15 antibody dependent cell mediated cytotoxicity |
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