参芪扶正注射液配合化疗治疗胃癌临床疗效观察 |
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引用本文: | 周柯鑫,王金华,刘宝宽,周春宇,辛明,植锦兰,李乃卿.参芪扶正注射液配合化疗治疗胃癌临床疗效观察[J].中国中西医结合杂志,1999,0(1):11-13. |
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作者姓名: | 周柯鑫 王金华 刘宝宽 周春宇 辛明 植锦兰 李乃卿 |
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作者单位: | 北京中医药大学附属东直门医院外科,丽珠集团利民制药厂研究所 |
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摘 要: | 目的:验证参芪扶正注射液的临床疗效。方法:随机分为3组比较疗法。化疗加参芪组(治疗组,化疗加静脉滴注参芪扶正注射液)62例,化疗对照组(化疗组,单用化疗)37例,单纯参芪组(参芪组,单用参芪扶正注射液)21例。观察疗效,并观察自然杀伤(NK)细胞、巨噬细胞及T细胞亚群等治疗前后变化。结果:治疗组对胃癌癌灶的缓解率为16.1%,稳定率为87.1%,化疗组为13.5%和64.9%,组间比较稳定以上率有
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关 键 词: | 参芪扶正注射液 胃癌 增效 减毒 治疗 |
Clinical Study on Effect of Shenqi Fuzheng Injection Combined with Chemotherapy in Treating Gastric Cancer |
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Authors: | Zhou Kexin Wang Jinhua Liu Baokuan Affiliated Dongzhimen Hospital Beijing University of Traditional Chinese Medicine Beijing |
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Abstract: | OBJECTIVE: To assess the clinical effect of Shenqi Fuzheng Injection (SQFZI) combined with chemotherapy in treating gastric cancer. METHODS: One hundred and twenty patients were randomly divided into 3 groups, the combined therapy group (Group A), the chemotherapy group (Group B) and the SQFZI group (Group C) and the effect on remission and stabilization of patients were observed. RESULTS: The remission rate and stabilizing rate of Group A were 16.1% and 87.1%, those of Group B were 13.5% and 64.9%, the difference between the two groups was significant, P < 0.05. The symptom and living quality improving rate of Group A were 75.8% and 43.5% respectively, those of Group C were 61.9% and 57.1% and of Group B were 35.1% and 29.7% respectively. SQFZI showed good protective effect on hemopoietic system, 4.8% patients in Group A with WBC count lower than 4 x 10(9)/L, while the percentage reached 21.6% in Group B, the difference between the two groups was significant, P < 0.05. Moreover, SQFZI could raise activity of NK cell, macrophage and T-lymphocyte subgroups, without any injury on heart, liver and kidney function or other adverse reaction. CONCLUSION: SQFZI combined with chemotherapy has certain effect of remission and stabilization on gastric cancer, the clinical effect is significant to patients with Qi-Deficiency, and is reliable and safe. |
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Keywords: | Shengqi Fuzheng Injection gastric cancer toxicity reducing and effect enhancing |
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