丹莪合剂治疗子宫内膜异位症的临床及实验研究

目的：寻找治疗子宫内膜异位症（内异症）既有效，副作用又少的药物。方法：应用纯中药制剂－丹莪合剂治疗内异症１８９例，观察治疗前后一些指标的变化，并且还观察了实验动物模型用丹莪合剂及丹那唑治疗后的情况。

Clinical and Experimental Study on the Treatment of Endometriosis with Dan'e Mixture

Objective: To find a medicine to treat endometriosis effectively with less side effect. Methods: Dan'e mixture (DEM, consists of Radix Salviae Miltiorrhizae and Rhizoma Zedoariae) was used to treat 189 cases of endometriosis and the change of symptom and sign, the B ultrasonograph, the anti endometrium antibody and endometriosis quantitative diagnostic index were observed, another 160 cases were treated with Danazol as control, also using animal model to treat with DEM and Danazol. Results: One hundred and eighty nine cases were treated for 9 months. According to National Standards, 39 cases (20.6%) were cured, 67 cases (35.4%) were markedly effective, 67 cases (35.4%) were effective, and 16 cases (8.4%) were ineffective. Compared with 160 cases treated with Danazol for 9 months, the total effective rates were 95% and 91.5% respectively, the difference between them was insignificant. Animal experiments showed the similar results to the clinical ones. Conclusion: SZM is a safe and effective medicine to treat endometriosis, which deserves further study and development. It is particularly helpful for diagnosis, treatment and prevention of endometriosis in the early stage.