盆腔炎颗粒对血瘀兼肾虚型慢性盆腔炎患者免疫学指标的影响 |
| |
引用本文: | 刘瑞芬,杨晓娜.盆腔炎颗粒对血瘀兼肾虚型慢性盆腔炎患者免疫学指标的影响[J].中国中西医结合杂志,2007,27(9):841-843. |
| |
作者姓名: | 刘瑞芬 杨晓娜 |
| |
作者单位: | 1. 山东中医药大学附属医院,济南,250011 2. 山东中医药大学 |
| |
基金项目: | 山东省中医药管理局资助项目 |
| |
摘 要: | 目的探讨盆腔炎颗粒对血瘀兼肾虚型慢性盆腔炎患者免疫学指标的影响。方法将60例血瘀兼肾虚型慢性盆腔炎患者随机分为治疗组(30例,服用盆腔炎颗粒)、对照组(30例,服用盆炎净颗粒),疗程均为4周。观察两组患者临床疗效和治疗前后外周血T细胞亚群水平、血清肿瘤坏死因子-α(TNF-α)以及白细胞介素-2(IL-2)浓度的变化。结果治疗组和对照组总有效率分别为96.7%和63.3%,两组比较差异有显著性(P〈0.05)。治疗组治疗后外周血CD4、CD4/CD8、血清IL-2较治疗前上升,CD8和血清TNF-α较治疗前下降(均P〈0.05),上述指标与对照组治疗后比较差异亦均有显著性(P〈0.05)。结论盆腔炎颗粒可提高血瘀兼肾虚型慢性盆腔炎患者免疫功能,减轻炎症。
|
关 键 词: | 盆腔炎颗粒 慢性盆腔炎 免疫功能 |
修稿时间: | 2006年6月7日 |
Effect of Penqiangyan Granule on the Immune Function of Patients with Chronic Pelvic Inflammatory Disease of Blood-stasis and Shen-deficiency Syndrome Type |
| |
Authors: | LIU Rui-fen and YANG Xiao-na |
| |
Abstract: | OBJECTIVE: To explore the effect of Penqiangyan Granule (PG) on the immunity of patients with chronic pelvic inflammatory disease (CPID) of blood stasis and Shen-deficiency syndrome (BSSDS) type. METHODS: Sixty patients were randomly assigned to two groups: the treatment group treated with PG and the control group with Penyanjing Granule, 30 cases in each group. The treatment course was 4 weeks for both groups. The clinical efficacy, plasma levels of CD4 and CD8, and the serum levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-2 (IL-2) were measured before and after treatment. RESULTS: After treatment, the total effective rate in the treatment group and the control group was 96.7% and 63.3% respectively with significant difference between groups (P < 0.05); in the treatment group the plasma CD4, CD4/CD8 and serum IL-2 increased obviously, while the plasma CD8 and serum TNF-alpha decreased markedly (P < 0.05), all were significantly different with those in the control group (P < 0.05). CONCLUSION: PG can improve the immune function and alleviate inflammation in CPID patients of BSSDS type. |
| |
Keywords: | Penqiangyan Granule chronic pelvic inflammatory disease immune function |
本文献已被 CNKI 维普 万方数据 等数据库收录! |
| 点击此处可从《中国中西医结合杂志》浏览原始摘要信息 |
| 点击此处可从《中国中西医结合杂志》下载免费的PDF全文 |