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健脾疏肝除湿化瘀法对腹泻型肠易激综合征患者近期生活质量影响的研究
引用本文:吴兵,张声生.健脾疏肝除湿化瘀法对腹泻型肠易激综合征患者近期生活质量影响的研究[J].中国中西医结合杂志,2008,28(10):894-896.
作者姓名:吴兵  张声生
作者单位:首都医科大学附属北京中医医院消化中心,北京,100010
基金项目:北京市科委科研基金,北京市首都发展基金
摘    要:目的 观察健脾疏肝、除湿化瘀法对腹泻型肠易激综合征(IBS D)患者近期生活质量的影响。 方法 125例IBS-患者分为3组,观察组采用以健脾疏肝、除湿化瘀立法的方药,随证加减;中成药组采用肠胃康颗粒、固本益肠片、补脾益肠丸、参苓白术丸辨证用药;西药组采用匹维溴胺50 mg、谷维素10 mg、培菲康420 mg,均每天3次口服;3组疗程均为4周;采用国际通用的SF-36生存量表对患者治疗前后的生活质量进行评估。

关 键 词:健脾疏肝除湿化瘀  腹泻型肠易激综合征  生活质量

Effect of TCM Therapy for Invigorating Pi,Soothing Gan,Eliminating Dampness and Resolving Blood Stasis on the Short-term Quality of Life in Patients with Diarrhea Type Irritable Bowel Syndrome
Authors:WU Bing and ZHANG Sheng-sheng
Abstract:Objective To observe the TCM therapy for invigorating Pi,soothing Gan,eliminating dampness and resolving blood stasis(TCM-T)on the short-term quality of life(stQOL)in patients with diarrhea type irritable bowel syndrome(IBS-D).Methods One hundred and twenty-five patients with IBS-D were assigned to 3 groups,Group A was treated with TCM-T;Group B treated with some selected Chinese patent drugs according to patients' syndrome types,such as Changweikang granule,Guben Yichang tablet,Bupi Yichang pill and Shenling Baizhu pill,Group C treated with Western medicines as Dicetel 50 mg,Oryzanol 10 mg,and Bifid triple viable 420 mg,3 times daily by oral administration.The therapeutic course was 4 weeks for all.The stQOL was evaluated and compared by SF-36 scale before and after treatment.Results Comparison between groups on the scores for the 8 dimensions of SF-36 scale,i.e.,physiological function(PF),role physical(RP),body pain(BP),global health(GH),vitality(VT),society function(SF),emotional effect(RE),and mental health(MH),showed no significant difference before treatment,but scores of all the 8 dimensions were improved significantly in Group A after treatment(P<0.05),with scores of SF,BP,GH and MH superior to those in Group B(P<0.05,P<0.01),and scores of RP,GH,SF,RE,PF and MH superior to those in Group C(P<0.05,P<0.01).Conclusion TCM-T has favorable effect in treating IBS-D,it could improve the stQOL of patients.
Keywords:invigorating Pi  soothing Gan  eliminating dampness and resolving blood stasis  diarrhea type irritable bowel syndrome  quality of life
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