肺癌国际生存质量量表与体能状态评定指标及中医症状量表的关系

目的从临床观察角度探讨国际生存质量量表与体能状态评估及中医症状量表之间的相互关系。方法采用欧洲癌症研究与治疗组织肺癌生存质量量表(EORTC QLQ—LC43)和癌症治疗功能评价量表(FACT—L)两种国际生存质量量表测定363例肺癌患者生存质量，同时记录其卡氏(KPS)评分与体能状态(ECOG)及肺癌中医症状量表(LCSL—TCM)计分，并作相关性及一致性分析。结果EORTC QLQ—LC43和FACT—L计分与KPS评分、ECOG及中医症状量表计分存在相关，但相关系数较小；各指标之间存在一致性。中医症状量表与KPS评分、ECOG之间不存在一致性。结论生存质量测评应采用生存质量量表，而不能以体能状态指标代替，但体能状态指标可作为生存质量的简易预测指标。中医症状量表与生存质量量表及体能状态指标之间有一定相关性。

Study on the Relationship among the International Scales for Quality of Life Evaluation in Patients with Lung Cancer,the East Cooperative Oncology Group Status and Lung Cancer Symptoms Lists of TCM

ObjectiveTo investigate the relationship among international scales for quality of life (QOL), physical performance assessment and Lung Cancer Symptoms Lists of Traditional Chinese Medicine (LCSL) from the viewpoint of clinical observation. MethodsQOL of 363 patients with lung cancer was estimated with two international scales, the European Organization for Research and Treatment of Cancer QOL Questionnaire LC-43 (EORTC QLQ-LC43) and the Functional Assessment of Cancer Therapy General and Lung (FACT-L). In the same time, scores calculated by Karnofsky Performance Status (KPS), East Cooperative Oncology Group Status (ECOG) and LCSL were recorded. Correlation and consistency among them were analyzed. ResultsEORTC QLQ-C43, FACT-L were correlated with KPS, ECOG and LCSL, but the correlation coefficient was small. All these indexes were consistent. ConclusionQOL should be assessed by QOL questionnaire, not by physical performance indexes, although they can be the simply forecast indexes of QOL. There is certain consistency between LCSL, QOL and physical performance.