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松龄血脉康胶囊联合卡托普利对原发性高血压病患者生活质量的影响
引用本文:陈伟强,陈富荣.松龄血脉康胶囊联合卡托普利对原发性高血压病患者生活质量的影响[J].中国中西医结合杂志,2001,21(9):660-662.
作者姓名:陈伟强  陈富荣
作者单位:1. 广东省佛山市中医院心血管内科
2. 广东省人民医院心血管研究所
摘    要:目的:比较单用卡托普利和联用松龄血脉康胶囊对原发性高血压病患者血压和生活质量的影响。方法:166例原发性高血压病患者随机分为联合组(联合用药)和卡托普利(单用卡托普利)两组。治疗1个月后血压达标者继续治疗5个月,进行生活质量量表评分,并与60名血压正常者作对照比较。结果:治疗1个月后,联合组、卡托普利组血压达标率分别为81.2%、60.2%,两组比较差异有显著性(P<0.01)。治疗前,两组高血压病患者除认知功能和社会参与两方面外,其余各方面与对照组比较,差异均有显著性(P<0.05,P<0.01)。联合组治疗后健康愉快感、躯体症状、工作表现、情感状态、生活满意度均较治疗前明显改善;卡托普利组治疗后健康愉快感、工作表现、情感状态、生活满意度较治疗前改善(P<0.05,P<0.01)。治疗后联合组在健康愉快感、躯体症状、工作表现、生活满意度方面与卡托普利组比较,差异有显著性(P<0.05,P<0.01)。结论:用松龄血脉康胶囊联合卡托普利治疗原发性高血压病,在有效降压的同时,可改善诸多临床症状、抑郁症状及工作表现,并能提高健康愉快感和生活满意度,在改善生活质量的多个方面优于单用卡托普利。

关 键 词:原发性高血压  松龄血脉康胶囊  卡托普利  生活质量  治疗
修稿时间:2001年2月14日

Effect of Songling Xuemaikang Capsule Combined with Captopril on Quality of Life in Primary Hypertension Patients
Authors:CHEN Wei  qiang and CHEN Fu  rong
Abstract:OBJECTIVE: To compare the hypotensive effects of captopril and combined medication of Songling Xue-maikang Capsule (SXC) with captopril on quality of life (QOL) in treating primary hypertension patients. METHODS: For 166 hypertension patients, a perspective randomized double blind study was performed with both sexes, aged 42-78 years, blood pressure (BP) ranged > or = 140/90 mmHg and < or = 200/110 mmHg. Patients were randomly divided into two groups: captopril group and combined medication group. Each patient should answer the QOL questionnaire independently before and after experiment. 60 age-matched normotensive subjects without chronic diseases served as control. RESULTS: Both hypertension groups showed an improvement of BP and QOL after treatment, but the combined medication group had a higher score in sense of well being, physical symptom-signs, work performance and life satisfaction than the captopril group had. CONCLUSION: Combined medication of captopril and SXC had better effect than captopril alone either in lowering BP or in improving QOL of primary hypertension patients.
Keywords:primary hypertension  Songling Xuemaikang Capsule  captopril  quality of life
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