番石榴叶治疗小儿轮状病毒肠炎的临床研究

目的：观察番石榴叶治疗小儿轮状病毒（HRV）肠炎的临床疗效。方法：62例HRV肠炎患儿随机分为治疗组和对照组，治疗组服用用番石榴叶，对照组服用葛根芩连汤。观察止泻时间：血清Na^+、粪Na^+、粪糖和HRV抗原转阴率。结果：治疗组3天治愈率为87.1%，对照组为58.1%，治疗组显著优于对照组（P<0.05）。治疗组止泻时间为(25.1±9.5)h,对照组为(38.7±15.2)h，治疗组止泻时间显著短于对照组（P<0.01）。治疗组粪Na^+、粪糖较治疗前明显下降，对照组下降不明显，治疗组优于对照组（ P<0.05）。治疗组粪HRV转阴率为87.1%，对照组为58.1%，治疗组显著优于对照组（P<0.05）。结论：番石榴叶治疗小儿HRV肠炎有比较好的疗效。

Clinical Study on Treatment of Infantile Rotaviral Enteritis with Psidium guajava L.

OBJECTIVE: To observe the clinical effect of olium Psidium guajava (PG) in treating infantile rotaviral enteritis. METHODS: Sixty-two patients of rotaviral enteritis were randomly divided into the treated group treated with PG and the control group treated with Gegen Qinlian decoction. The time for ceasing diarrhea, the content of Na+ in blood, the content of Na+ and glucose in stool, and the rate of negative conversion of human rotavirus (HRV) antigen were observed. RESULTS: The rate of recovery in 3 days of the treated group was 87.1%, significantly higher than that of the control group (58.1%, P < 0.05). The time of ceasing diarrhea of the treated group (25.1 +/- 9.5 hr) was significantly shorter than that of the control group (38.7 +/- 15.2 hr, P < 0.01). The content of Na+ and glucose in stool was reduced obviously in the treated group, while the reduction in the control group was insignificant, the treated group was superior to the control group significantly (P < 0.05). The rate of negative conversion of HRV in feces of the treated group was 87.1%, significantly better than that of the control (58.1%, P < 0.05). CONCLUSION: The treatment with PG has good curative effect on infantile rotaviral enteritis.