活血益气养阴方防治急性放射损伤的研究

目的：用活血益气养阴中药减轻放疗急性毒副反应。方法：７２例鼻咽癌患者分成两组，各３６例，均行根治性放疗，放疗中实验组（Ａ组）服用中药活血益气养阴方。对照组（Ｂ）组维斯克含漱或外敷。结果：口腔粘膜和皮肤损伤Ａ，Ｂ两组各为４７．２％（１７／３６例），９１．７％（３３／３６例），１３．９％（５／３６例），３３．３％（１２／３６例）；损伤各不相同。

Study of Prevention and Treatment on Acute Radioactive Injury with Huoxue Yiqi Yangyin Recipe

OBJECTIVE: To reduce the acute toxic and side-effect of radiotherapy with Huoxue Yiqi Yangyin recipe (HYYR). METHODS: Seventy-two nasopharyngeal carcinoma patients that using radiotherapy were divided into two groups: HYYR group (A) and the control group (B) using Wisk lotion for gargling or apply at the skin lesion. RESULTS: The injury on mucous membrane of mouth cavity and skin were 47.2%, 91.7%, 13.9%, 33.3% in group A and B respectively, the degree of injury was different (P < 0.01). The acute reaction of the mucous membrane of mouth cavity did not occur until the cumulative radiation were 41.4 +/- 9.4, 30.9 +/- 8.9 in group A and B respectively, there was significant difference between the two groups (P < 0.01). CONCLUSION: HYYR can reduce the acute radioactive reaction of the skin and mucous membrane of mouth cavity and inhibition of bone marrow.