中西医结合治疗老年人原发性肾病综合征临床观察 |
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引用本文: | 魏连波,叶任高,陈旭红,李智军,吕瑞和,栾图.中西医结合治疗老年人原发性肾病综合征临床观察[J].中国中西医结合杂志,2000,20(2):99-101. |
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作者姓名: | 魏连波 叶任高 陈旭红 李智军 吕瑞和 栾图 |
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作者单位: | 第一军医大学南方医院中医内科!广州510515(魏连波,李智军,吕瑞和),中山医科大学肾脏病研究所(叶任高),广东省残联培训中心(陈旭红,栾图) |
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摘 要: | 目的:观察中西医结合治疗老年人原发性肾病综合征(INS)的临床疗效。方法:82例老年人INS患者随机分为治疗组和对照组。治疗组(41例)有强的松和环磷酰胺(CTX)并辨证加服中药,对照组(41例)单纯用西药治疗。观察临床缓解率、副反应率、副发率及缓解时间。结果:治疗组完全缓解率(58.5%)和总缓解率(85.4%)均显著高于对照组(39.0%、63.4%,P〈0.01)。治疗组副反应率(36.6%
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关 键 词: | 老年人 肾病综合征 中西 医结合治疗 |
Clinical Observation of Elderly Idiopathic Nephrotic Syndrome Treated with Integrated Traditional Chinese and Western Medicine |
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Authors: | L Wei R Ye X Chen |
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Institution: | Nanfang Hospital, First Military Medical University, Guangzhou (510515). |
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Abstract: | OBJECTIVE: To observe the clinical effect of integrated traditional Chinese and western medicine (TCM-WM) in treating the elderly idiopathic nephrotic syndrome (INS). METHODS: Eighty-two patients of the elderly INS were randomly divided into the TCM-WM group and the control group. Forty-one patients of the TCM-WM group were treated with prednisone, Cytoxan (CTX) and Chinese medicinal herbs according to Syndrome-type, the other 41 patients of the control group were treated with WM alone. Clinical remission rate, adverse reaction, recurrence rate and remission period were observed. RESULTS: The complete remission rate and total remission rate of the TCM-WM group were 58.5% and 85.4%, significantly higher than those of the control group (39.0%, 63.4%, P < 0.01). The adverse reaction rate of the TCM-WM group (36.6%) was significantly lower than that of the control group (80.5%, P < 0.01). A follow-up of 35.1 +/- 9.7 months showed that there was no significant difference in the recurrence rate between two groups (P > 0.05), but the average remission period (30.6 +/- 3.8 months) of the TCM-WM group was significantly longer than that of the control group (12.7 +/- 3.7 months, P < 0.01). CONCLUSION: TCM-WM treatment is obviously superior to treatment with WM alone in increasing clinical remission rate, relieving adverse reaction rate and extending remission period. |
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Keywords: | integrated traditional Chinese and western medicine elderly idiopathic nephrotic syndrome |
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