输卵管介入术配合补肾活血法治疗输卵管阻塞性不孕症的临床观察

目的 比较输卵管介入术配合补肾活血法与单纯输卵管介入术治疗输卵管阻塞性不孕症的疗效。方法 两组均于月经净后3～7天内行输卵管介入术，并于下个月经周期常规行宫腔输卵管通液术1次，注入香丹注射液40ml。治疗组于月经周期第5天开始加服补肾活血剂，每天1剂，每月连服14剂。3个月为1个疗程，共观察4个疗程。结果 两组治疗后卵泡发育情况、子宫内膜厚度、排卵前期血清雌二醇（E2）值与本组治疗前比较，差异均有显著性（P〈0．05，P〈0．01）；且治疗组优于对照组（P〈0．05，P〈0．01）。治疗组妊娠率高于对照组，两者比较差异有显著性（P〈0．05）。结论 输卵管介入术配合补肾活血法是治疗输卵管阻塞性不孕症的有效方法，能明显改善输卵管阻塞性不孕患者的卵泡发育及宫内膜生长，且显著提高妊娠率。

Effects of Combined Therapy of Salpingostomy and Bushen Huoxue Drugs on Fallopian Tube Obstructive Infertility

ObjectiveTo compare the effect of treatment of fallopian tube obstructive infertility by salpingostomy alone and in combination with TCM drugs for Bushen Huoxue (invigorating Shen and promoting blood circulation). MethodsTo all the patients, salpingostomy was performed 3 to 7 days after menstruation and hydrotubation with Xiangdan Injection (XI) was applied once in the next menstrual cycle. Bushen Huoxue Decoction (BHD) was administrated additionally to patients in the treated group, 1 dose every day starting from the 5th day of menstrual cycle for 14 days. Three months' treatment was taken as one therapeutic course and the observation lasted for 4 courses. Results The condition of follicular development, thickness of endometrium and level of serum estradiol in the preovulatory phase after treatment were all significantly increased in the two groups (P<0.05 and P<0.01); but the improvement in the treated group was significantly superior to that in the control group, showing significant difference. Moreover, the pregnancy rate was also higher in the former than in the latter (P<0.05). Conclusion The combined therapy of salpingostomy and TCM drugs for invigorating Shen and promoting blood circulation is an effective therapy for fallopian tube obstructive infertility, it has the effect of enhancing follicular development and increasing thickness of endometrium, and could elevate the pregnancy rate in patients.