| 海冬花粉对营养性肥胖小鼠的影响 |
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| 引用本文： | 王卫霞,王巍,孙斌辉,赵德忠,高普.海冬花粉对营养性肥胖小鼠的影响[J].中国中西医结合杂志,2001(Z1). |
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| 作者姓名： | 王卫霞 王巍 孙斌辉 赵德忠 高普 |
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| 作者单位： | 中国中西医结合杂志社 (北京100091)(王卫霞)，中国中医研究院西苑医院老年医学研究所 (北京100091)(王巍，孙斌辉，赵德忠，高普) |
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| 基金项目： | 国家中医药管理局资助项目(No.95B1284) |
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| 摘 要： | 目的:探讨药食同源的海冬花粉对营养性肥胖小鼠减肥作用的机理。方法:用摄入热量过多造成的小鼠肥胖模型观察海冬花粉的药效及其机理。结果:海冬花粉可降低肥胖小鼠的 Lee′s 指数(P<0.01,P<0.05);降低血糖含量(P<0.01,P<0.05);对耐缺氧、耐疲劳能力均无明显影响;厌食试验阴性;粪便性状无变化。结论:海冬花粉具减肥作用,其减肥不致厌食和腹泻,不影响体力。其减肥机理可能与调节糖代谢有关。
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| 关 键 词： | 海冬花粉 营养性肥胖模型 减肥 降糖 常压下耐缺氧和耐疲劳能力 |
Study on Effects of Haidonghua Powder on Nutritive Obesity in Mice |
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| Authors: | WANG Wei-xia WANG Wei SUN Bin-hui |
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| Abstract: | Objective:To study the mechanism of weight reducing effect of Haidonghua Powder(HDHP) consisted of Laminaria japonica,Ben- incasa hispida.Methods:The model of obesity made by calorie hyperphagia of mice was used to observe the pharmacologic effect and mechanism of HDHP.Randomly divided into 5 groups:normal group,control group,large dosage HDHP group,small dosage HDHP group and positive drug control group.Results:HDHP could reduce the Lee's index of obesity mice (P<0.01) and lower the content of blood glucose,but showed no influence on hypoxia and fatigue resistance,with negative anorexia test and no change in property of stool. Conclusion:HDHP has a body weight reducing effect without lowering of physical strength and side-effect of anorexia and diarrhea,the mechanism might be related to the glucose metabolism regulation. |
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| Keywords: | Haidonghua Powder nutritive obesity body weight reducing hypoglycemic hypoxia and fatigue resistance under normal atmospheric pressure |
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