大承气冲剂对人体胃肠运动功能的影响

目的：观察大承气冲剂对某些消化道运动功能障碍性疾病的治疗作用，并阐明其作用机理。方法：应用消化道灌注测压、胃电图描记、胃动素的放免测定、口-盲传输时间测定等手段，直接观察大承气冲剂对人体消化道运动功能的影响。结果：大承气冲剂可显著改善术后胃电节律的紊乱，提高移动性运动复合波(migrating motor complex，MMC)Ⅲ期的幅度和时间，减少胃肠逆蠕动的发生，增加血中胃动素水平，减少口-盲传输时间，促进胃肠运动功能的恢复。结论：大承气冲剂是有效的胃肠动力药，服用方便，可用于消化道运动障碍疾病的治疗。

Effect of Dachengqi Granule on Human Gastrointestinal Motility

OBJECTIVE: To study the therapeutic effect and mechanism of Dachengqi granule (DCQG) on some digestive motility disturbed diseases. METHODS: Gastroduodenojejunal manometry, electrogastrography (EGG), RIA of motilin and orocecal transit time test were applied to directly observe the effect of DCQG on human gastrointestinal motility. RESULTS: DCQG could significantly improve the postoperational EGG disorder, elevate the amplitude and time of migrating motor complex (MMC) phase III, prevent gastrointestinal reversed peristalsis, increase the blood level of motilin, decrease the orocecal transit time, and promote the recovery of gastrointestinal motility. CONCLUSION: DCQG is an effective digestive kinetic agent, which could be medicated conveniently in treating digestive motility disturbed diseases.