番泻叶浸剂灌肠在腹部手术后应用的临床与实验研究

目的：探讨番泻叶侵剂治疗腹部手术后胃肠道功能紊乱的疗效及其机理。方法：患者腹部手术后灌肠给番泻叶侵剂，观察术后腹部功能恢复情况，并进行了动物实验。结果：经治疗１３０例患者腹部手术后在加快肠鸣音出现和恢复，缩短排气、排便时间，减少切口感染等方面疗效显著。动物实验结果表明：该药对大鼠在体肠管运动有明显的增强作用（Ｐ〈０．０１）；有显著的增强离体大鼠回肠蠕动和增大收缩振幅的作用（Ｐ〈０．０５）；对在体小

Clinical and Experimental Study on Using Cassia Angustifolia Extract as Enema after Abdominal Operation

Objective: To investigate the curative effect and mechanism of using Cassia angustifolia extract (CAE) in treating gastrointestinal tract dysfunction after abdominal operations. Methods: Enema administration of CAE (Clyster method) was used. Results: The result of 130 patients was very effective in reducing the rate of gastrointestinal decompression, accelerating the restitution of borborygmi and the time of exhaustion. Animal experiment showed the CAE function is very obvious in enhancing the bowel movement of rats (P<0 05). It can enhance peristalsis and contraction amplitude of vibration in the isolated ileum of rats (P<0 05). It can push on the charcoal powder in intestinal tract of mice obviously (P<0 05). Conclusion: CAE could regulate disordered function of gastrointestinal tract after abdominal operations.