中西医结合治疗扩张型心肌病的临床观察

目的：观察中西医结合治疗扩张型心肌病的疗效。方法：对320例临床诊断扩张型心肌病患者随机分为两组，治疗组164例，用中西医结合治疗（黄芪、生脉、牛磺酸、泛葵利酮及强心、利尿、扩血管等），对照组156例，用常规治疗（极化液、泛葵利酮及强心、利尿、扩血管等）。结果：治疗组临床症状的好转明显高于对照组（P＜0．01），心功能改善优于对照组（P＜0．05）。随访中两组死亡总数基本相似，但治疗3－6个月内对照组死亡人数明显多于治疗组。而治疗组中坚持治疗1年者，1年后的死亡人数明显低于治疗3－6个月者（分别为1例及11例）。结论：在目前对扩张型心肌病无明显特效药物治疗的情况下，采用中西医结合治疗不失为一种可取的药物治疗手段。

Observation on Collaborative Treatment of Dilated Cardiomyopathy

OBJECTIVE: To observe the therapeutic effect of integrated traditional Chinese and western medicine (TCM-WM) in treating dilated cardiomyopathy (DCM). METHODS: Patients of DCM were randomly divided into two groups, the 164 patients in the TCM-WM group were treated with combination therapy of traditional Chinese and western medicine, consisting of conventional western medicine, such as cardiac diuretic, vasodilative agents, taurine, coenzyme Q10, antiarrhythmics, beta blockers and Chinese herbal preparations such as Astragalus membranaceus and Shengmai injection; while the 156 cases in the control group were treated with conventional western medicine alone, including polarized liquid therapy, etc. RESULTS: The improvement of clinical symptoms and heart function in the TCM-WM group was significantly better than that in the control group. Although the total number of deceased cases in the two groups were similar, the dead number in 3-6 months in the TCM-WM group was less than that in the control group. Moreover, 1 year later, the deceased number of patients insisted with TCM-WM treatment for over 1 year was significantly less than in those treated for only 3-6 months (1 case vs 11 cases). CONCLUSION: Under the condition that there is no specific effective drugs, TCM-WM therapy can yet be regarded as an acceptable therapy for treatment of dilated cardiomyopathy.