| 经皮穴位电刺激对慢性运动性疲劳大鼠的影响(英文) |
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| 引用本文： | 方剑乔,马桂芝,梁宜,王臻.经皮穴位电刺激对慢性运动性疲劳大鼠的影响(英文)[J].针灸推拿医学(英文版),2012,10(5):265-270. |
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| 作者姓名： | 方剑乔 马桂芝 梁宜 王臻 |
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| 作者单位： | Zhejiang University of Traditional Chinese Medicine, Hangzhou 310053, China |
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| 基金项目： | This work was supported by National Natural Science Foundation of China （30572412）; Top Priority Discipline of Zhejiang Province （Acupuncture-moxibustion and Tuina）. |
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| 摘 要： | 目的:观察经皮穴位电刺激(Transcutaneous Electrical Acupoint Stimulation,TEAS)对运动性疲劳大鼠的影响。方法:采用递增负荷跑台法建立大鼠慢性运动性疲劳模型,第6星期开始,分别在运动后即刻和3h后进行TEAS治疗。治疗2星期后,HE染色观察大鼠海马、下丘脑组织形态学变化,免疫组化法观察海马、下丘脑5-羟色胺(5-hydroxytryptamine,5-HT)的表达。结果:TEAS可以明显减轻运动引起的大鼠海马、下丘脑组织形态损伤,降低大鼠海马、下丘脑5-HT表达,运动后即刻治疗和3h后治疗的两组间无统计学差异。结论:TEAS有促进疲劳恢复,提高运动能力的作用。TEAS改善大鼠的运动性疲劳状态与降低中枢5-HT表达、减少神经细胞损伤有关。
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| 关 键 词： | 穴位疗法 肌肉疲劳 5-羟色胺 海马 下丘脑 大鼠 |
Effect of transcutaneous electrical acupoint stimulation on rats with chronic exercise-induced fatigue |
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| Fang Jian-qiao
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Ma Gui-zhi
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Liang Yi
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Wang Zhen.Effect of transcutaneous electrical acupoint stimulation on rats with chronic exercise-induced fatigue[J].Journal of Acupuncture and Tuina Science,2012,10(5):265-270. |
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| Authors: | Fang Jian-qiao Ma Gui-zhi Liang Yi Wang Zhen |
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| Institution: | 1. Zhejiang University of Traditional Chinese Medicine, Hangzhou, 310053, China
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| Abstract: | Objective To observe the effect of transcutaneous electrical acupoint stimulation (TEAS) on the rats with exercise-induced fatigue. Methods Rat model of chromic exercise-induced fatigue was established with increasing load treadmill walking method. The TEAS therapy was operated immediately and 3 h after the exercise from the sixth week. Hippocampal morphology and hypothalamic morphology were observed with HE staining and the expressions of 5-hydroxytryptamine (5-HT) in hippocampus and hypothalamus were tested with immunohistochemical (IHC) staining after 2-week treatment. Results TEAS released the damage of hippocampal morphology and hypothalamic morphology induced by exercise significantly and reduced the expression of 5-HT in hippocampus and hypothalamus. The difference between the therapy operated immediately and 3 h after exercise was not significant. Conclusion TEAS could improve the fatigue recovery and athletic ability. The improvement of TEAS on the rats with exercise-induced fatigue was related with the decreased expression of central 5-HT and the reduction of damaged nerve cells. |
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| Keywords: | Acupoint Therapy Muscle Fatigue Serotonin Hippocampus Hypothalamus Rats |
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