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介入治疗后ACS患者中医证候要素分布特征的现况调查
引用本文:杨巧宁,谷丰,高铸烨,史大卓.介入治疗后ACS患者中医证候要素分布特征的现况调查[J].中国中医急症,2014(1):6-8.
作者姓名:杨巧宁  谷丰  高铸烨  史大卓
作者单位:[1]中国中医科学院研究生院,北京100700 [2]中国中医科学院西苑医院心血管病研究所,北京100091
基金项目:国家“十一五”科技攻关课题(2006BAI04A01);国家“重大新药创制”科技重大专项(2009ZX09502-031);中医药行业科研专项(201007001)
摘    要:目的调查介入治疗后急性冠脉综合征(ACS)患者中医证候要素的分布规律。方法采用横断面研究设计.ACS患者于介人治疗成功后24—48h内调查其病史、症状、体征及证候要素特点,利用冠心病中医临床科研共享系统进行数据录入和管理.应用SPSS13.0进行统计分析。结果共调查5家医院480例介入治疗成功的ACS患者,其中血瘀占81.7%,痰浊偏寒占22.5%,痰浊偏热占18.3%,气虚占51.7%,阴虚占42.5%,阳虚占10.8%。证候要素组合情况显示:2个证候要素相兼占52.5%,3个证候要素相兼占23.3%,单证候要素占14.2%,4个证候要素占10.0%。其中血瘀与痰浊(包括偏寒与偏热)相兼占34.2%,血瘀与气虚相兼占44.2%,血瘀与阴虚相兼占32.5%.气虚与阴虚相兼占26.7%。结论介入治疗后ACS患者证候要素主要是血瘀、气虚,证候要素组合以2个证候要素组合最常见,其中以血瘀兼气虚组合最常见。

关 键 词:急性冠脉综合征  介入治疗  证候要素  

Distribution and Combination Characteristics of TCM Syndrome Elements in Acute Coronary Syndrome Patients with Percutaneous Coronary Intervention
Institution:YANG Qiao-ning,GU Feng,GAO Zhu-ye,et al. 1 China Academy of Chinese Medical Sciences ,Beijing 100700,China;2 Xiyuan Hospital,China Academy of Chinese Medical Sciences , Beijing 100091, China
Abstract:Objective: To investigate the distribution and combination characteristics of TCM syndrome elements in acute coronary syndrome (ACS) patients with percutaneous coronary intervention (PCI). Methods: The ACS cases diagnosed by coronary arteriongraphy in 24-48 hours were collected and made TCM syndrome elements differentiation based on medical history ,symptom and sign. The SPSS 13.0 software statistics was used in data analysis. Results: 480 ACS cases were involved. The asthenia in superficiality proportions of the disease nature of syndrome elements from high to low were as follows:blood stasis in 81.7%, cold turbid phlegm in 22.5%, heat turbid phlegm in 18.3%. The asthenia in origin proportions in the disease narure were:qi deficiency in 51.6% ,yin deficiency in 42.5%,yang deficiency in 10.8%.In the elments combination form: 2 disease nature elements combined occupied 52.5%. 3 disease nature elements combined was 23.3%. The single element account for 14.2%, the proportion of four disease nature elementscombined was 10.0%. In the specific combination,blood stasis and turbid phlegm including cold and heat accounted for 34.17% ,blood stasis and qi deficiency made up 44.17%, blood stasis and yin deficiency accounted for 32.5% ,qi and yin deficiency accounted for 26.67%. Conclusion: The main syndrome elments are blood stasis,qi deficiency. 2 syndrome elments combined is the most common, which blood stasis and qi deficiency take the largest proportion.
Keywords:ACS  PCI  Syndrome elements  Sydrome
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