| 加味大承气汤灌肠治疗多器官功能障碍综合征患者肠道黏膜屏障功能障碍临床研究 |
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| 引用本文： | 张锐,林琳,鲁召欣,韩洁,李正光,邱志鹏,赵海蓉. 加味大承气汤灌肠治疗多器官功能障碍综合征患者肠道黏膜屏障功能障碍临床研究[J]. 中国中医急症, 2011, 20(4): 524-525,577 |
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| 作者姓名： | 张锐 林琳 鲁召欣 韩洁 李正光 邱志鹏 赵海蓉 |
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| 作者单位： | 1. 山东省青岛市海慈医疗集团,山东,青岛,266000
2. 山东省青岛市急救中心,山东,青岛,266000 |
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| 基金项目： | 山东省青岛市医药科研指导计划课题 |
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| 摘 要： | 目的观察加味大承气汤灌肠对多器官功能障碍综合征患者肠道黏膜屏障功能障碍的治疗作用。方法将患者40例随机分为A组与B组,均予常规西医治疗,在此基础上A组予以大承气汤液灌肠,B组予安慰剂灌肠。两组治疗7d。比较两组治疗前、治疗第3日及第7日的尿乳果糖/甘露醇比值（L/M）和循环D-乳酸质量浓度。结果治疗组尿（L/M）和循环D-乳酸的下降大于对照组。结论加味大承气汤灌肠治疗可改善多器官功能障碍综合征患者肠道黏膜通透性,保护肠黏膜屏障功能。
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| 关 键 词： | 多器官功能障碍综合征 肠黏膜屏障功能 尿乳果糖/甘露醇比值 D-乳酸 大承气汤 |
Study of Modified Dachenggi Decoction Enema Therapy on Intestinal Mucous Membrane Barrier Dysfunction of Patients with Multiple Organ Dysfunction Syndrome |
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| ZHANG Rui,LIN Lin,LU Zhao-xin,et al Haiser Medical Group of Qingdao,Sh,ong Province. Study of Modified Dachenggi Decoction Enema Therapy on Intestinal Mucous Membrane Barrier Dysfunction of Patients with Multiple Organ Dysfunction Syndrome[J]. Journal of Emergency in Traditional Chinese Medicine, 2011, 20(4): 524-525,577 |
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| Authors: | ZHANG Rui LIN Lin LU Zhao-xin et al Haiser Medical Group of Qingdao Sh ong Province |
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| Affiliation: | ZHANG Rui,LIN Lin,LU Zhao-xin,et al Haiser Medical Group of Qingdao,Shandong Province(Qingdao 266033,Shandong) |
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| Abstract: | Objective:To observe the therapeutic effect of Modified Dachengqi Decoction enema therapy on intestinal mucous membrane barrier dysfunction of patients with multiple organ dysfunction syndrome.Methods:40 cases with multiple organ dysfunction syndrome and intestinal mucous membrane barrier dysfunction were randomly divided into the A group and the B group.Beside of conventional treatment,the A group was used the enema therapy of Modified Dachengqi Decoction once a day.The B group was given to the placebo ene... |
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| Keywords: | Multiple organ dysfunction syndrome Intestinal mucosa barrier function Urinary lactulose/mannitol value D-lactic acid Dachengqi Decoction |
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