前列腺增生症中医证型与IPSS、PSA、Qmax的相关性研究

目的评价前列腺增生症(BPH)常见3种中医证型与国际前列腺症状评分(IPSS)、最大尿流率(Qmax)、前列腺特异抗原(PSA)的相关性。方法 130例年龄50~85岁BPH患者,根据《中药新药临床研究指导原则评分标准》BPH常见3种中医证型(本研究特定为肾气亏虚证、血瘀下焦证、膀胱湿热证3种证型),并对患者的证型与IPSS、Qmax、PSA之间进行相关性分析。结果肾气亏虚证、血瘀下焦证、膀胱湿热证3种BPH中医证型与IPSS评分密切相关,BPH常见3种中医证型与Qmax、PSA无相关性。结论 BPH常见3种中医证型与IPSS评分存在一定的相关性。

Correlation Study of TCM Syndrom,IPSS,PSA and Qmax in the Benign Prostatic Hyperplasia

Objective: To evaluate the relevance amoung the TCM syndrome,the International Prostate Symptom Score(IPSS),the maximum urinary flow rate(Qmax) and the prostate-specific antigen(PSA) of benign prostate hyperplasia(BPH).Methods: 130 cases of patients with BPH were analysed on the relevance amount 3 types of common TCM syndrome,including the syndrome of deficiency of kidney qi,the syndrome of blood stasis in lower jiao and the syndrome of dampness-heat in bladder,the IPSS,the Qmax and the PSA of BPH.Results: Those 3 syndromes were closely relevant to IPSS,but they were no relevance with Qmax and PSA.Conclusion: 3 types of common TCM syndrome have relevance with IPSS.