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参芪扶正注射液联合化疗对非小细胞肺癌患者外周血细胞水平及免疫细胞活性的影响
引用本文:孙一予,马少军,贾英杰,张莹,陈亮.参芪扶正注射液联合化疗对非小细胞肺癌患者外周血细胞水平及免疫细胞活性的影响[J].中国中医急症,2007,16(7):776-777.
作者姓名:孙一予  马少军  贾英杰  张莹  陈亮
作者单位:天津中医药大学第一附属医院,天津,300193
摘    要:目的 观察参芪扶正液联合化疗对非小细胞肺癌患者外周血细胞水平及免疫细胞活性的影响。方法 选择Ⅲ-Ⅳ期非小细胞肺癌患者采用TP方案联合参液扶正液治疗34例,与单用TP方案28例进行治疗前后T细胞亚群及NK细胞活性的检测与比较,并比较两组的血液毒性反应。结果 治疗组其细胞免疫能力不同程度提高,而对照组免疫能力下降,两组有显著性差异;前者血细胞无明显下降,毒副反应较轻,生活质量明显改善。结论 参芪扶正注射液可作为晚期肺癌化疗的辅助用药以提高机体免疫功能,降低化疗后毒副反应的发生率。

关 键 词:非小细胞肺癌  参芪扶正注射液  化疗  免疫功能
文章编号:1004-745X(2007)07-0776-02
收稿时间:2007-02-27
修稿时间:2007-02-27

Effects of Cellular Immunity State of Body and Toxic Effect of The Treatment by Chemotherapy Combined with Shenqi -fuzheng Injection used for Non Small Cell Lung Cancers
SUN Yi-yu, MA Shao-jun, JIA Ying-jie, et al.Effects of Cellular Immunity State of Body and Toxic Effect of The Treatment by Chemotherapy Combined with Shenqi -fuzheng Injection used for Non Small Cell Lung Cancers[J].Journal of Emergency in Traditional Chinese Medicine,2007,16(7):776-777.
Authors:SUN Yi-yu  MA Shao-jun  JIA Ying-jie  
Institution:The First Affiliated Hospital to Tianjin University of Traditional chinese Medicine ( Tianjin 300193
Abstract:Objective:To observe the clinical effects of cellular immunity state of body and toxic effect of the treatment by chemotherapy combined with Shenqi-fuzheng injection used for non small cell lung cancers(NSCLC). Methods:34 cases with NSCLC were given Shenqi-fuzheng injection combined with TP chemotherapeutic protocol (group A),28 cases were given TP chemotherapy only(group B).The ability ofT cell and NK cell were examined in both group after treatment,and the toxic effect were also been compared.Results:The ability of immunocyte was improved in group A,while it was weakened in group B.There was statistical significance.Compared with group B, group A had lower toxic effects.Conclusion:Shenqi-fuzheng injection can improve the ability of immunity of body and reduce toxic effects when used in advanced NSCLC.
Keywords:NSCLC  Shenqi -fuzheng injection  Chemotherapy  Cell immunity
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