| 萝芙木属植物药理活性和单萜吲哚生物碱合成途径研究进展 |
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| 引用本文： | 陈晓英,郭晓云,李翠,李莹,姚绍嫦,张占江,蓝祖栽.萝芙木属植物药理活性和单萜吲哚生物碱合成途径研究进展[J].中草药,2019,50(8):2004-2012. |
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| 作者姓名： | 陈晓英 郭晓云 李翠 李莹 姚绍嫦 张占江 蓝祖栽 |
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| 作者单位： | 广西壮族自治区药用植物园 广西药用资源保护与遗传改良重点实验室, 广西南宁 530023,广西壮族自治区药用植物园 广西药用资源保护与遗传改良重点实验室, 广西南宁 530023,广西壮族自治区药用植物园 广西药用资源保护与遗传改良重点实验室, 广西南宁 530023,广西壮族自治区药用植物园 广西药用资源保护与遗传改良重点实验室, 广西南宁 530023,广西壮族自治区药用植物园 广西药用资源保护与遗传改良重点实验室, 广西南宁 530023,广西壮族自治区药用植物园 广西药用资源保护与遗传改良重点实验室, 广西南宁 530023,广西壮族自治区药用植物园 广西药用资源保护与遗传改良重点实验室, 广西南宁 530023 |
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| 基金项目： | 广西科学研究与技术开发计划项目（桂科攻0424008-1J）；广西科技计划项目（桂科AD17292004）；北京市计算中心云计算关键技术与应用北京市重点实验室课题：药用植物资源信息化在防伪溯源中的应用研究 |
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| 摘 要： | 萝芙木属植物中的蛇根木是印度传统草药,目前萝芙木属植物成为中国常用南药,主要用于治疗高血压、精神类疾病、心血管疾病、癌症等。对国产萝芙木属植物资源种类及分布、药理活性、萝芙木单萜吲哚生物碱的合成途径等研究进展进行综述,为萝芙木属植物的研究和临床应用提供参考。
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| 关 键 词： | 萝芙木属 蛇根木 单萜吲哚生物碱 生物合成途径 关键酶 |
| 收稿时间： | 2019/1/14 0:00:00 |
Research progress on pharmacological properties and monoterpenoid indole alkaloids biosynthetic pathway in plants of genus Rauvolfia |
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| CHEN Xiao-ying,GUO Xiao-yun,LI Cui,LI Ying,YAO Shao-chang,ZHANG Zhan-jiang and LAN Zu-zai.Research progress on pharmacological properties and monoterpenoid indole alkaloids biosynthetic pathway in plants of genus Rauvolfia[J].Chinese Traditional and Herbal Drugs,2019,50(8):2004-2012. |
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| Authors: | CHEN Xiao-ying GUO Xiao-yun LI Cui LI Ying YAO Shao-chang ZHANG Zhan-jiang and LAN Zu-zai |
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| Institution: | Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China,Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China,Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China,Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China,Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China,Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China and Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China |
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| Abstract: | Rauvolfia serpentine is a traditional Indian medicine and now the genus Rauvolfia becomes a commonly used south medicine in China. Rauvolfia is mainly used to treat hypertension, mental illness, cardiovascular disorders, cancer, and other diseases. The paper overviewed the main species and distribution, pharmacological properties, and the monoterpenoid indole alkaloids biosynthetic pathway of Rauvolfia in China. The paper aims to provide reference for research and clinical application in plants of the genus Rauvolfia. |
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| Keywords: | Rauvolfia Linn Rauvolfia serpentina (Linn ) Benth ex Kurz monoterpenoid indole alkaloids biosynthetic pathways key enzymes |
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