中药凝胶贴膏剂的研究进展及在产品开发中的应用

中药凝胶贴膏作为经皮给药系统的重要组成部分,一方面继承了中医药的传统理论,同时又结合现代制剂新工艺、新技术,在近年来发展迅速。与传统的黑膏剂、橡胶膏剂相比,中药凝胶贴膏采用水溶性高分子材料作为基质,具有保湿性能好,与皮肤相容性好,亦可反复贴敷等优势,越来越受到科研工作者的重视。同时中药凝胶贴膏也面临着基质配比不合理、制备工艺简陋、质量评价体系不完善等诸多问题。通过查阅近年来中药凝胶贴膏的相关文献,从发展现状、基质组成、制备工艺等方面进行综述,为中药凝胶贴膏的深入研究提供参考和借鉴。

Research progress on Chinese materia medica gel plaster and its application in product development

As an important part of transdermal drug delivery system, gel plaster of Chinese materia medica (CMM) has inherited the traditional theory of traditional Chinese medicine and developed rapidly in recent years in combination with the new technology and technology of modern preparations. Compared with the traditional black paste and rubber paste, the gel plaster of CMM, which uses water-soluble polymer as the matrix, has the advantages of good moisturizing performance, good compatibility with the skin, and repeated patching. It has been paid more and more attention by researchers. At the same time, the gel plaster of CMM also faces many problems, such as unreasonable matrix ratio, simple preparation process, and imperfect quality evaluation system. This article reviews the development status, matrix composition, and preparation technology of gel plaster of CMM in recent years, and provides reference for the further study of gel plaster of CMM.