| 蛋白质组学在中药现代化研究中的应用 |
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| 引用本文： | 王志平,乔建军,元英进.蛋白质组学在中药现代化研究中的应用[J].中草药,2004,35(1):1-4. |
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| 作者姓名： | 王志平 乔建军 元英进 |
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| 作者单位： | 天津大学化工学院,制药工程系,天津,300072 |
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| 基金项目： | 国家 8 63计划资助项目 (863 -2 0 0 1AA2 14 0 81)，国家自然科学基金资助项目 (3 0 2 0 0 0 0 3 ) |
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| 摘 要： | 根据国内外文献，结合课题组应用蛋白质组学对药物合成途径及代谢调控的研究，介绍研究蛋白质组学的主要内容、技术手段，以及在中药现代化研究中的巨大应用意义，并分析了蛋白质组学的未来发展方向，为中药现代化以及新型中药制剂的开发提供参考。蛋白质组学将成为中药现代化研究中必不可少的工具之一。
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| 关 键 词： | 蛋白质组学 中药现代化 基因组学 二维凝胶电泳 药物靶点 |
| 文章编号： | 0253-2670(2004)01-0001-04 |
| 收稿时间： | 2003/5/27 0:00:00 |
| 修稿时间： | 2003年5月27日 |
Application of proteomics to modernization research of Chinese materia medica |
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| WANG Zhi-ping,QIAO Jian-jun and YUAN Ying-jin.Application of proteomics to modernization research of Chinese materia medica[J].Chinese Traditional and Herbal Drugs,2004,35(1):1-4. |
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| Authors: | WANG Zhi-ping QIAO Jian-jun and YUAN Ying-jin |
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| Institution: | Pharmaceutical Engineering Department,College of Chemical Engineering,Tianjin University,Tianjin 300072,China;Pharmaceutical Engineering Department,College of Chemical Engineering,Tianjin University,Tianjin 300072,China;Pharmaceutical Engineering Department,College of Chemical Engineering,Tianjin University,Tianjin 300072,China |
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| Abstract: | To summarize the application of proteomics to modernization research of Chinese materia medica (CMM) and offer the reference for modernization of CMM and new medicine preparation exploitation. Based on the references and our project group studies in proteomic of drug biosynthesis pathway and metabolization;the main content,technology strategies and important application of the proteomics were introduced significantly;and the further development of protemics was analyzed. The proteomics will become one of absolutely necessary tackles in the modernization research of CMM. |
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| Keywords: | proteomics modernization of Chinese materia medica genomics two-dimension gel electrophoresis drug target |
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