| 喙荚云实中-个新二萜类化合物 |
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| 引用本文： | 吴兆华.喙荚云实中-个新二萜类化合物[J].中草药,2008,39(8):1127-1129. |
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| 作者姓名： | 吴兆华 |
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| 作者单位： | 牡丹江医学院药学系,黑龙江,牡丹江,157011 |
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| 摘 要： | 目的研究喙荚云实Caesalpinia minax的化学成分。方法采用多种色谱方法分离纯化,依据理化性质、波谱数据分析进行结构鉴定。结果从喙荚云实的95%乙醇溶液回流提取物中分离鉴定了一个呋喃二萜类化合物minaxin A,并利用MTT法研究这个化合物对人肝癌细胞HepG2的生长抑制作用。结论该化合物为新化合物,药理活性实验结果表明minaxin A对人肝癌细胞HepG2具有一定的生长抑制作用。
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| 关 键 词： | 喙荚云实 minaxin A 人肝癌细胞 抑制活性 |
| 收稿时间： | 3/2/2008 12:00:00 AM |
A novelditerpenefromCaesalpiniaminax |
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| WU Zhao-hua.A novelditerpenefromCaesalpiniaminax[J].Chinese Traditional and Herbal Drugs,2008,39(8):1127-1129. |
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| Authors: | WU Zhao-hua |
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| Institution: | Department of Pharmacy, Mudanjiang Medical University, Mudanjiang 157011, China |
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| Abstract: | Objective To study the chemical constituents of Caesalpinia minax.Methods The chemical constituents were isolated and purified by various chromatographic methods and their structures were elucidated by the analysis of spectral data and physicochemical properties.Results One diterpene compound was isolated from the 95% alcohol extract of C.minax,which was named minaxin A,and the inhibitoryactivitiesofthecompoundonHepG2cellwerestudiedbyuseofMTTmethod.ConclusionMinaxin A is a new compound and shows the significant inhibitory activities on HepG2 cell. |
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| Keywords: | Caesalpinia minax Hance minaxin A HepG2 cell inhibitory activities |
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