| 三七止血活性与商品规格划分的相关分析 |
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| 引用本文： | 山丽梅,赵艳玲,洪玮,张萍,孔维军,刘志国,肖小河.三七止血活性与商品规格划分的相关分析[J].中草药,2011,42(9):1779-1782. |
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| 作者姓名： | 山丽梅 赵艳玲 洪玮 张萍 孔维军 刘志国 肖小河 |
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| 作者单位： | 1. 解放军302医院中药研究所,北京,100039
2. 解放军302医院临床检验中心,北京,100039 |
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| 基金项目： | 国家中医药管理局基金，“重大新药创制”科技重大专项资助项目，国家公益性行业科研专项基金 |
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| 摘 要： | 目的探讨三七止血活性与商品规格划分的相关性。方法小鼠ig给予不同商品规格三七后,测定剪尾出血时间(BT)及凝血时间(CT),并采用全自动血液分析仪测定凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、纤维蛋白原(FIB)和计数血小板(PLT),同时采用HPLC法测定不同商品规格三七中三七素的量,分析三七止血活性与商品规格划分的相关性及与三七素量的关系。结果不同商品规格三七能明显缩短小鼠BT和CT、增加PLT数量、缩短PT和APTT,止血活性与商品规格划分无相关性,其中无数头三七粉剂止血效果最明显;不同商品规格三七中三七素的量存在差异,其中无数头三七中三七素质量分数最高达0.98%,80头质量分数最低仅为0.52%,与止血活性和商品规格划分无相关性。结论三七商品规格划分与止血活性及三七素的量无相关性,但是不同商品规格三七中以价格低廉的无数头三七素的量最高,也以无数头三七止血活性最佳,价格昂贵的13头和20头三七止血活性并非最好。
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| 关 键 词： | 三七 商品规格 止血活性 三七素 凝血时间 |
| 收稿时间： | 2010/11/5 0:00:00 |
Correlation analysis between hemostatic activity and commercial grades of Panax notoginseng |
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| SHAN Li-mei,ZHAO Yan-ling,HONG Wei,ZHANG Ping,KONG Wei-jun,LIU Zhi-guo and XIAO Xiao-he.Correlation analysis between hemostatic activity and commercial grades of Panax notoginseng[J].Chinese Traditional and Herbal Drugs,2011,42(9):1779-1782. |
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| Authors: | SHAN Li-mei ZHAO Yan-ling HONG Wei ZHANG Ping KONG Wei-jun LIU Zhi-guo and XIAO Xiao-he |
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| Institution: | SHAN Li-mei1,ZHAO Yan-ling1,HONG Wei2,ZHANG Ping1,KONG Wei-jun1,LIU Zhi-guo2,XIAO Xiao-he1 1.Institute of Chinese Materia Medica,The 302 Hospital of PLA,Beijing 100039,China 2.Center for Clinical Laboratory,Chin |
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| Abstract: | Objective To explore the correlation between the hemostatic activity and commercial grades of Panax notoginseng.Methods After treatment with different commercial grades of P.notoginseng,the mice blooding time(BT) and clotting time(CT) were measured.At the same time the prothrombin time(PT),activation part thrombin time(APTT),fibrinogen(FIB),and platelet count(PLT) were also detected by fully automated blood cell analyzer.The contents of dencichine were determined by HPLC.Results Mice BT,CT,PT,and APTT were ... |
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| Keywords: | Panax notoginseng(Burk ) F H Chen commercial grades haemostatic activity dencichine clotting time(CT) |
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