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微波萃取对不同形态结构中药及含不同极性成分中药的选择性研究
引用本文:沈岚,冯年平,韩朝阳,朱沪平,范广平.微波萃取对不同形态结构中药及含不同极性成分中药的选择性研究[J].中草药,2002,33(7):604-607.
作者姓名:沈岚  冯年平  韩朝阳  朱沪平  范广平
作者单位:上海中医药大学,上海,200032
基金项目:清华大学化学工程国家联合重点实验室开放课题
摘    要:目的 探索微波萃取(ME)对不同形态结构中药及含不同极性成分中药的提取规律。方法 以大黄,决明子中不同极性的蒽醌类成分及金银花中绿原酸,黄芩中黄芩苷为指标成分,以HPLC法测定,采用正交试验设计法分别考察提取率,结果 ME对大黄中不同极性蒽醌成分的提取选择性并不明显,而同一温度条件下,根茎类中药大黄中大黄素,大黄酚,大黄素甲醚的提取率明显高于种子类中药决明子中相同成分的提取率。结论 ME对不同形态结构中药的提取有选择性,对含不同极性成分中药的提取选择性不显著。

关 键 词:正交试验设计  微波萃取  HPLC法  中药提取
文章编号:0253-2670(2002)07-0604-04
收稿时间:9/3/2001 12:00:00 AM
修稿时间:2001年9月3日

Selectivity of microwave extraction on Chinese medicines in different morphological structure and different polar compositions
Shen Lan,Feng Nianping,Han Zhaoyang,Zhu Huping and Fan Guangping.Selectivity of microwave extraction on Chinese medicines in different morphological structure and different polar compositions[J].Chinese Traditional and Herbal Drugs,2002,33(7):604-607.
Authors:Shen Lan  Feng Nianping  Han Zhaoyang  Zhu Huping and Fan Guangping
Institution:Shanghai University of TCM, Shanghai 200032, China;Shanghai University of TCM, Shanghai 200032, China;Shanghai University of TCM, Shanghai 200032, China;Shanghai University of TCM, Shanghai 200032, China;Shanghai University of TCM, Shanghai 200032, China
Abstract:Object To explore the regularity of microwave extraction (ME) on Chinese medicines in different morphological structure and different polar compositions. Methods Anthraquinone in Radix et Rhizoma Rhei (RRR), Semen Cassiae (SC), cholorogenic acid in Flos Lonicerae, baicalin in Radix Scutellariae were determined as index compositions by HPLC. The extraction rate was measured by orthogonal design. Results ME selectivity to different anthraquinone in RRR is not significant, while at the same temperature, the extraction rates of emodin, chrysophanol, physcion in RRR are higher than those in SC. Conclusion The ME selectivity to the different morphological structure of Chinese medicines is obvious, but to the different polar compositions is not distinct.
Keywords:microwave extraction (ME)  Chinese medicines  selectivity  orthogonal design  
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