三棱的化学成分研究

目的分离鉴定三棱Sparganii Rhizoma的化学成分,为后期的体外活性筛选提供样品。方法应用色谱技术分离纯化,通过理化性质和波谱学方法鉴定化合物的结构。结果从三棱95%乙醇提取物中分离得到12个化合物,分别鉴定为过氧化麦角甾醇(1)、(8E,10E)-7,12-二氧-8,10-十八碳二烯酸(2)、α-二十一烷酸单甘油酯(3)、正丁酸(4)、大黄素甲醚(5)、香草醛(6)、大黄素(7)、香草酸(8)、对羟基苯甲酸(9)、反丁烯二酸(10)、1-O-阿魏酰基-3-O-p-香豆酰基甘油(11)、赤藓醇(12)。结论化合物1～5、7、9、10和12为首次从黑三棱属植物中分离得到。

Chemical constituents from Sparganii Rhizoma

Objective To elucidate the chemical constituents from Sparganii Rhizoma and provide samples for activity screening.Methods Column chromatographic techniques were used and the structures of the constituents were elucidated on the basis of physicochemical properties and spectral data.Results Twelve compounds were isolated and identified as ergosterol peroxide(1),(8E,10E)-7,12-dioxo-8,10-octadecadienoic acid(2),glycerol-α-heneicosanoate(3),betulinic acid(4),physcion(5),vanillin(6),emodin(7),vanillic acid(8),p-hydroxybenzoic acid(9),trans-butene diacid(10),1-O-feruloyl-3-O-p-coumaroylglycerol(11),and erythritol(12).Conclusion Compounds 1—5,7,9,10,and 12 are obtained from the plants of Sparganium L.for the first time.