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黄酮类中药单体成分治疗类风湿性关节炎作用机制研究进展
引用本文:刘维,孙淳,吴沅皞.黄酮类中药单体成分治疗类风湿性关节炎作用机制研究进展[J].中草药,2014,45(19):2878-2882.
作者姓名:刘维  孙淳  吴沅皞
作者单位:天津中医药大学第一附属医院, 天津 300193;天津中医药大学, 天津 300193;天津中医药大学第一附属医院, 天津 300193
基金项目:国家自然科学基金面上项目(81273709);天津市高等学校科技发展基金计划(20120220)
摘    要:类风湿性关节炎属于中医“痹证”范畴,中药治疗类风湿关节炎历史悠久,并且在临床中取得了确切的疗效。相关中药单体成分治疗类风湿性关节炎的药理学研究取得了较大进展,其中黄酮类单体成分具有一定的代表性。因此,对黄酮类中药单体成分治疗类风湿性关节炎的作用机制进行综述。

关 键 词:黄酮类单体成分  中药  类风湿性关节炎  细胞因子  作用靶点
收稿时间:5/8/2014 12:00:00 AM

Research progress on mechanism of flavonoid monomers isolated from Chinese materia medica for rheumatoid arthritis treatment
LIU Wei,SUN Chun and WU Yuan-hao.Research progress on mechanism of flavonoid monomers isolated from Chinese materia medica for rheumatoid arthritis treatment[J].Chinese Traditional and Herbal Drugs,2014,45(19):2878-2882.
Authors:LIU Wei  SUN Chun and WU Yuan-hao
Institution:The First Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;The First Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Abstract:Rheumatoid arthritis (RA) belongs to "arthralgia syndrome" in the field of traditional Chinese medicine (TCM). Chinese materia medica has been confirmed to be an effective therapy in long-term TCM clinical practice to treat RA. Progress in the pharmacology research of Chinese medicinal monomers has been made in recent years. This paper reviews the mechanism of flavonoid monomers isolated from Chinese materia medica for RA treatment.
Keywords:flavonoid monomer  Chinese materia medica  rheumatoid arthritis  cell factor  target
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