| 香薷的研究进展及其质量标志物预测分析 |
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| 引用本文： | 姚奕,许浚,黄广欣,张铁军,刘昌孝.香薷的研究进展及其质量标志物预测分析[J].中草药,2020,51(10):2661-2670. |
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| 作者姓名： | 姚奕 许浚 黄广欣 张铁军 刘昌孝 |
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| 作者单位： | 天津中医药大学, 天津 300193;中药现代制剂与质量控制技术国家地方联合工程实验室, 天津 300301;天津市中药质量标志物重点实验室, 天津 300301;天津药物研究院 释药技术与药物代谢动力学国家重点实验室, 天津 300301 |
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| 基金项目： | 国家自然科学基金资助项目（81830111）;"中医药现代化研究"重点专项（2019YFC1711200） |
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| 摘 要： | 香薷作为常用解表中药,其化学成分多样,临床应用十分广泛。对香薷进行本草考证、化学成分和主要药理活性总结,并在此基础上结合质量标志物(Q-marker)的核心概念,从生源途径、传统药性药效、药动学和体内过程以及可测成分等方面对香薷Q-marker进行预测分析,为其质量评价提供了理论依据。
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| 关 键 词： | 香薷 化学成分 药理活性 质量标准 质量标志物 |
| 收稿时间： | 2020/1/3 0:00:00 |
Research progress of Moslae Herba and predictive analysis on its Q-marker |
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| YAO Yi,XU Jun,HUANG Guang-xin,ZHANG Tie-jun,LIU Chang-xiao.Research progress of Moslae Herba and predictive analysis on its Q-marker[J].Chinese Traditional and Herbal Drugs,2020,51(10):2661-2670. |
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| Authors: | YAO Yi XU Jun HUANG Guang-xin ZHANG Tie-jun LIU Chang-xiao |
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| Institution: | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;National & Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine, Tianjin 300301, China;Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine, Tianjin 300301, China;State Key Laboratory of Drug Delivery and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin 300301, China |
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| Abstract: | As a commonly used Chinese medicine, Moslae Herba has a diversity of chemical composition and is extensively used in clinical applications. In this paper, the researches on materia medica, chemical compositions, and pharmacological activities of Moslae Herba were summarized. Based on the core concepts of Q-marker, Q-marker components of Moslae Herba were forecasted and analyzed from original source, traditional pharmacodynamics, pharmacokinetics, in vivo process, and measurable composition, which provides a theoretical basis for its quality evaluation. |
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| Keywords: | Moslae Herba chemical constituent pharmacological activity quality standard quality marker |
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