| 甜茶素对小鼠糖异生作用和血脂代谢的影响 |
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| 引用本文： | 田翠平,瞿伟菁,等.甜茶素对小鼠糖异生作用和血脂代谢的影响[J].广西中医药,2001,24(4):59-61. |
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| 作者姓名： | 田翠平 瞿伟菁 |
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| 作者单位： | 华东师范大学生命科学院!200062上海市中山北路3663号 |
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| 基金项目： | 上海市科技发展基金资助项目(NO.003912074) |
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| 摘 要： | 目的 :研究甜茶素对小鼠糖异生作用和血脂代谢的影响。方法 :雄性昆明种小鼠22只 ,随机分为对照组和给药组。给药组小鼠每天灌胃甜茶素 ,对照组小鼠灌胃生理盐水。灌胃3周后 ,测小鼠的血清葡萄糖、血清甘油三酯、血清胆固醇及肝糖原等生化指标。结果 :甜茶素能降低正常小鼠血糖水平 ,降糖率为18.47 % ;其对小鼠糖异生具有明显的抑制作用 ,抑制率为17.32%。同时 ,甜茶素能明显降低血清甘油三酯水平 ,降低幅度为30.08% ;对胆固醇含量也有降低作用。结论 :甜茶素对小鼠血糖代谢的影响与控制糖异生途径有关。
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| 关 键 词： | 甜茶素 血清葡萄糖 糖异生 血脂代谢 实验研究 |
EFFECT OF RUBUSOSIDE ON MICE GLUCONEOGENESIS AND METABOLISM OF BLOOD LIPID |
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| TianCuiping QuWeijing Zhang WenWangHong LiMingjuan ShcoolofLifeScienceEastChinaNormalUniversity, ZhongshanBeiRoadShanghai.EFFECT OF RUBUSOSIDE ON MICE GLUCONEOGENESIS AND METABOLISM OF BLOOD LIPID[J].Guangxi Journal of Traditional Chinese Medicine,2001,24(4):59-61. |
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| Authors: | TianCuiping QuWeijing Zhang WenWangHong LiMingjuan ShcoolofLifeScienceEastChinaNormalUniversity ZhongshanBeiRoadShanghai |
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| Institution: | TianCuiping QuWeijing Zhang WenWangHong LiMingjuan ShcoolofLifeScienceEastChinaNormalUniversity,200062 3663ZhongshanBeiRoadShanghai |
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| Abstract: | Ojective:Tostudytheeffectofrubusosideongluconeogenesisandbloodlipidmetabolisminmice Method:22malemiceweredivided intocontrolgroupandmedicatinggrouprandomly Themiceofmedicatinggroupweregivenrubusosideeverydayandthemiceofthecontrolgroup weregivenphysiologicalsaline After3weeks,thelevelofserumglucoe,serumtriglyceride,serumcholsterolandtheliverglycogeninmicewere determined Result:Thelevelofbloodsugarcouldbereducedsignificantlybyrubusosidewitharateof18 47 % Thegluconeogensiscanbein hibitedbyrubusosideobviouslywitharateof17 32 %,rubusosidedecreaedthelevelofserumtriglyceridemarkedlywitharateof30 08 %andit alsoreducedthecontentofserumcholsterol Conclusion:Theeffectofrubusosideonbloodsugarmetabolismmayberelatedtothecontrolof gluconeogenesispathavay |
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| Keywords: | Rubusoside SerumGlucose Gluconeogenesis blood -lipidmetabolism Experimentalstudy |
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