基于药效物质基础的中药药物代谢动力学

中药药物代谢动力学（中药药动学）研究是近年来兴起的中药研究的新领域，研究了一些中药和复方，提出了一些相关的理论假说，但总体上尚处于初期的探索阶段，需进一步地深入研究。本文总结与评述了中药药动学近年来的研究进展，探讨了中药药动学的概念、中药药动学研究的特点与难点，从而提出了基于药效物质基础的中药药动学研究模式的设想。

Material Basis-based Pharmacokinetic Investigation of Chinese Medicine

The pharmacokinetic study of Chinese medicine (CM) is a new research direction in recent years. The pharmacokinetics of some CM and its formula have been investigated and a number of related theories and hypotheses have been proposed, which provide some insights into this area. However, the overall studies in this aspect were still at the early exploratory stage and further studies are needed. This paper summarizes the recent advances, interprets the definition, characteristics and difficulties of CM pharmacokinetic study. The authors proposed the material basis-based evaluation model for CM pharmacokinetic study.