| 慢性疼痛中枢调控网络的研究现状与思考＊ |
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| 引用本文： | 陶偲钰,武平,唐洁,蒋楠楠,汪雪,帅柔纤,胡新悦.慢性疼痛中枢调控网络的研究现状与思考＊[J].世界科学技术-中医药现代化,2022,24(1):258-264. |
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| 作者姓名： | 陶偲钰 武平 唐洁 蒋楠楠 汪雪 帅柔纤 胡新悦 |
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| 作者单位： | 成都中医药大学针灸推拿学院 成都 610075,成都中医药大学针灸推拿学院 成都 610075,成都中医药大学针灸推拿学院 成都 610075,成都中医药大学针灸推拿学院 成都 610075,成都中医药大学针灸推拿学院 成都 610075,成都中医药大学针灸推拿学院 成都 610075,成都中医药大学针灸推拿学院 成都 610075 |
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| 基金项目： | 国家自然科学基金项目（面上项目，重点项目，重大项目） |
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| 摘 要： | 慢性疼痛是一种复杂的身心疾病，包括躯体痛觉异常、认知障碍、负性情绪等多个方面的改变，同时伴随着神经系统的功能以及结构的改变。本文将对慢性疼痛与下行疼痛调节通路、疼痛情感-认知调控网络以及中脑边缘奖赏网络的相关性，以及针刺镇痛的中枢机制相关研究文献进行综述，旨在探讨下行疼痛调节通路、疼痛情感-认知调控网络以及中脑边缘奖赏网络在慢痛发生机制中的作用，为临床治疗慢性疼痛类疾病提供更优势的治疗方案。
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| 关 键 词： | 慢性疼痛 中枢调控网络 针刺治疗 |
| 收稿时间： | 2021/2/9 0:00:00 |
| 修稿时间： | 2022/4/9 0:00:00 |
Analysis and Consideration of the Central Nervous Mechanism of Chronic Pain |
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| Tao Siyu,Wu Ping,Tang Jie,Jiang Nannan,Wang Xue,Shuai Rouqian and Hu Xinyue.Analysis and Consideration of the Central Nervous Mechanism of Chronic Pain[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2022,24(1):258-264. |
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| Authors: | Tao Siyu Wu Ping Tang Jie Jiang Nannan Wang Xue Shuai Rouqian and Hu Xinyue |
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| Institution: | School of Acupuncture, Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China,School of Acupuncture, Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China,School of Acupuncture, Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China,School of Acupuncture, Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China,School of Acupuncture, Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China,School of Acupuncture, Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China,School of Acupuncture, Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China |
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| Abstract: | Chronic pain is a complex physical and mental disease, including physical pain abnormalities, cognitive impairment, negative emotions and other aspects of the change, accompanied by the nervous system function and structure changes. This article reviewed the correlation between chronic pain and the neural mechanisms, including the descending control mechanisms, the modulation of pain by cognitive-emotional network and mesolimbic dopamine system, as well as the central nervous mechanism of acupuncture. It explored the role of the descending control mechanisms, the modulation of pain by cognitive-emotional network and mesolimbic dopamine system in the pathogenesis of chronic pain, and provide superior treatment plan for clinical treatment of chronic pain diseases. |
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| Keywords: | Chronic pain The central nervous mechanism Acupuncture |
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