糖尿病前期中医证型及证素特点分析＊

目的 探讨糖尿病前期的中医证型及证素分布特点。方法 检索中国知网、万方及维普三大数据库中收录的自建库以来有关糖尿病前期证型的临床研究文献,对中医证型进行规范整理,建立数据库,提取证素,运用数据挖掘技术中的关联分析、聚类分析探究证素分布规律。结果 共纳入10篇文献,总有效病例1620例,证型经规范处理后整理为18个,主要证型为脾虚痰湿证。共提取证素13个,主要病位证素为脾,主要病性证素为气虚、湿和痰,关联分析显示脾—湿支持度和置信度最高,聚类分析结果可得到3个聚类组。结论 糖尿病前期病位在脾,气虚、脾、痰、湿是常见证素,临床诊治糖尿病前期应注重从脾论治,需辨证施治。

Analysis of Prediabetes Traditional Chinese Medicine Syndrome and Syndrome Elements

Objective To explore the characteristics of TCM syndromes and syndrome elements of prediabetes.Methods We searched the clinical research literature on prediabetes syndrome since the establishment of the database included in the three major databases of CNKI, Wanfang and VIP, standardized the syndromes, established a database, extracted the syndrome elements, and used data mining techniques in correlation analysis and cluster analysis to explore the distribution of syndrome elements.Results A total of 10 literatures were included, with a total of 1620 cases. After standardizing the syndromes, they were sorted into 18 syndromes. The main syndrome was spleen deficiency and phlegm dampness. We collected 13 syndrome elements. The main disease location syndrome element was spleen, and the main disease syndrome element was qi deficiency, phlegm and dampness. Correlation analysis showed that the spleen-phlegm support and confidence were the highest, and cluster analysis showed that 3 cluster groups could be obtained.Conclusion Prediabetes is located in the spleen. Qi deficiency, spleen, phlegm and dampness are common syndrome elements. The clinical diagnosis and treatment of prediabetes should focus on the treatment of the spleen and syndrome differentiation.