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| 不同穴位针刺对进行性力竭游泳大鼠免疫平衡的保护作用 | |
| 作者姓名： | Zhang W Zhao GG Su LQ Zheng Li X Zhi-Hong Y |
| 作者单位： | 1. 江西中医学院体育教学部,南昌,330004 2. 南昌大学教育学院体育系,南昌,330031 3. 江西中医学院基础医学院,南昌,330004 4. 江西中医学院现代中药制剂教育部重点实验室,南昌,330004 |
| 基金项目： | 江西省教育厅科学技术研究项目 |
| 摘 要： | 目的:观察"足三里"或"血海"穴位针刺对大强度运动大鼠免疫失衡的干预作用,探讨不同穴位的相对特异性。方法:32只雄性SD大鼠随机分为正常组、模型组、血海组与足三里组,每组8只。其中模型、血海、足三里组进行为期13 d的递增负荷游泳训练,血海、足三里组每日训练结束20 min后进行20 min的穴位针刺干预。各组大鼠实验结束后8 h取股动脉血与脾脏,采用ELISA法测定血清干扰素-γ(IFN-γ)、白介素-4(IL-4)含量,用电子天平称重脾脏。结果:与模型组比较,血海组、足三里组第1次力竭游泳时间延长(P<0.01,P<0.05)。与正常组相比,模型组脾脏指数及血清IFN-γ、IFN-γ/IL-4水平均降低(P<0.01,P<0.05);与模型组相比,血海组与足三里组血清IL-4含量降低(P<0.05,P<0.01),足三里组IFN-γ、IFN-γ/IL-4水平升高(P<0.05,P<0.01);足三里组血清IFN-γ含量高于血海组(P<0.05)。结论:针刺"足三里"能延长进行性力竭游泳大鼠的力竭时间,上调血清IFN-γ含量和IFN-γ/IL-4比例,这可能与其纠正大强度运动所导致的Th1/Th2失衡有关;针刺"足三里"的效果比"血海"明显。 |
| 关 键 词： | 针刺 力竭实验 干扰素-γ 白细胞介素-4 干扰素-γ/白细胞介素-4 |
Effect of acupuncture of different acupoints on immune function in rats with exhausted swimming |
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| Zhang W,Zhao GG,Su LQ,Zheng Li X,Zhi-Hong Y.Effect of acupuncture of different acupoints on immune function in rats with exhausted swimming[J].Acupuncture Research,2011,36(3):181-186. | |
| Authors: | Zhang Wei Zhao Guang-Gao Su Li-Qiang Zheng Li Xiang Zhi-Hong Yan |
| Institution: | ZHANG Wei,ZHAO Guang-gao1,SU Li-qiang,ZHENG Li-xiang2,YAN Zhi-hong3(Department of Sports Education,Jiangxi College of Chinese Medicine,Nanchang 330004,China,1Department of Sports of Education College,Nanchang University,Nanchang 330031,2School of Basic Medical Science,3Key Lab of Modern Chinese Drugs Preparation of the Ministry of Education,Nanchang 330004) |
| Abstract: | Objective To observe the effect of acupuncture of Zusanli(ST 36) on immune function in progressively exhausted swimming rats so as to reveal its mechanism underlying improvement of strenuous exercise.Methods Thirty-two SD rats were randomly allocated into control group,strenuous exercise(model) group,acupuncture-Xuehai(SP 10) group,Acupuncture-Zusanli(ST 36) group(n=8/group).The rats were forced to have a swimming in a water tank for 15-90 min in the first 8 days(once daily),then,a progressively exhausted l... |
| Keywords: | Acupuncture Strenuous exercise Serum IFN-γ IL-4 IFN-γ/IL-4 |
| 本文献已被 CNKI 万方数据 PubMed 等数据库收录！ | |