| 电针对大鼠脑缺血后脑内神经细胞凋亡的影响 |
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| 引用本文： | 晏义平,孙凤艳.电针对大鼠脑缺血后脑内神经细胞凋亡的影响[J].针刺研究,1998,23(1):33-35. |
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| 作者姓名： | 晏义平 孙凤艳 |
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| 作者单位： | 广东省汕头大学医学院药理教研室!汕头515031(晏义平)，上海医科大学医学神经生物学国家重点实验室!上海200032(孙凤艳) |
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| 摘 要： | 本研究运用TUNEL染色法观察电针对大鼠脑缺血后脑内神经细胞凋亡的影响。结果显示：在假手术组和单纯电针组，大鼠脑内未见神经细胞凋亡，脑缺血后12小时，大脑皮层梗塞区内大量的神经细胞凋亡，在缺血十电针组，大脑皮层梗塞区内神经细胞凋亡数目显著减少。结果表明：电针抑制脑缺血后脑内神经细胞凋亡。
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| 关 键 词： | 脑缺血 凋亡 电针 |
Effect of Electro-acupuncture on Neuronal Death Induced by Focal Cerebral Ischemia in Rats |
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| Abstract: | In this study, TUNEL staining was used to observe the effect of electro-acupuncture(EA) on apoptotic neuronal death induced by focal cerebral ischemia in rats. The results were as follows: In the sham-operated group and the EA treated group, TUNEL positive stained cell was not detected in the brain. In the ischemic group, a large number of apoptotic neuronal cells were detected in the infarcted area of cerebral cortex at 12h postischemia. In the ischemia + EA treated group, the number of apoptotic neuronal cells in the infarcted area reduced significantly. The results suggest that EA inhibits apoptotic neuronal death induced by focal cerebral ischemia. |
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