切断胃经沿线脂肪条带结构对针刺“足三里”镇痛作用的影响

目的:观察大鼠胃经沿线脂肪条带结构与胃经镇痛功能的相关作用。方法:SD大鼠16只,在大鼠胃经沿线脂肪条带结构上手术切除6 mm长一段,1周后针刺“后三里”,测定针刺前后痛阈,并与术前、非手术侧、对照组针刺痛阈进行对比。结果:切断大鼠胃经沿线脂肪条带结构,针刺前后的痛阈未产生有统计学意义的变化,与术前、非手术侧和对照组针刺痛阈变化对比具有显著意义。结论:大鼠胃经沿线脂肪条带结构与胃经镇痛功能密切相关。

Influence of Sectioning Fat-strip along the Stomach Meridian on Acupuncture Analgesia

Objective: To observe the influence of sectioning fat-strip along the Stomach Meridian on acupuncture analgesia.Methods: Sixteen SD rats were randomized into control group(n=6) and treatment group(n=10).After anesthesia with 3% pentobarbital((40 mg/kg)),a 6 mm long fat strip 6-(8 mm) proximal to "Zusanli"(ST 36)] along the Stomach Meridian of each rat in treatment group was excised,while for rats of control group,a same length of muscle strip beside the fat strip was removed.In treatment group,ST-36 was punctured with the acupuncture needle manipulated with uniform reinforcing-reducing method for(15 min).Pain threshold(tail flick latency responding to warm water stimulation) was detected before acupuncture,(0 min),(10 min),(20 min),(30 min) and(60 min) after acupuncture.Results: In control group,the pain threshold values between pre-and post-acupuncture before and after operation on the operation side,and between pre-and post-acupuncture on the non-operation side had no significant differences(P>0.05).There was a significant difference between control group and treatment group in the pain threshold on the operation side after acupuncture(P<0.001).In treatment group,the pain threshold values between pre-and post-acupuncture on the operation side had no significant difference(P>0.05);while those between pre-and post-acupuncture before operation,and between pre-and post-acupuncture on the non-operation side,and between operation side and non-operation side had significant differences(P<0.001),suggesting that after removal of the fat-strip along the Stomach Meridian,acupuncture induced increase of the pain threshold was abolished.Conclusion: The fat-strip structure along the Stomach Meridian is closely related to acupuncture of "Zusanli"(ST 36) induced analgesia.