“神阙”穴隔药灸对荷瘤化疗大鼠胃肠功能影响的实验研究

本实验从胃肠激素和胃肠病理学等方面研究了“神阙”穴隔药灸对荷瘤化疗大鼠胃肠功能的保护作用。结果表明,“神阙’穴隔药灸可避免荷瘤化疗大鼠胃粘膜变薄,防止粘膜上皮坏死及浅层腺体剥脱,并能提高血清胃泌素、胃动素、胃粘膜胃泌素水平。证实“神阙”穴隔药灸可有效地减轻化疗药物的毒性作用,保护胃肠功能。

The Experimental Research on the Effect of Drug-partitioned Moxibustion at "Shenque"on the Gastrointestinal Function of Tumor-bearing Chemotherapy Rat

In this experiment, the gastrointestinal hormones and pathology were used as indices to research the protective effect of drug-partitioned moxibustion at "Shenque" (RN 8)on the function of gastrointestinal tract in tumor-bearing chemotherapy rats. The results show that the way drug-partitioned moxibustion at "Shenque"(RN 8) can avoid thinning gastric mucosa, prevent the necrosis of epithelial cells and superficial glands from exfoliating, and can also raise the levels of serum gastrin, serum motilin and gastrin of gastric mucosa. As a result, the repair of gastric mucosa is promoted and the gastrointestinal dynamic is adjusted. The experiment has proved that this method can effectively alleviate the gastrointestinal toxic reaction of chemotherapeutic drug (5-Fu) and protect the gastrointestinal functions.