| 银黄冲剂中黄芩甙在家兔体内的代谢动力学研究 |
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| 引用本文： | 张志荣,胡晓颖.银黄冲剂中黄芩甙在家兔体内的代谢动力学研究[J].中成药,1996,18(6):1-3. |
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| 作者姓名： | 张志荣 胡晓颖 |
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| 作者单位： | 华西医科大学 |
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| 摘 要： | 采用反相高效液相色谱法测定了口服单剂量银黄冲剂后，家兔体内黄芩甙的血药曲线，并据此研究了银黄冲剂中黄芩甙在体内代谢动力学规律。结果表明，黄芩甙在家兔体内的代谢符合二室药动学模型。并求出了该制剂的主要药动学参数。
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| 关 键 词： | 银黄冲剂，黄芩甙，药代动力学，HPLC |
Metabolic Kinetic Study on Baicalin of Yinhuang Granules(Flos Lonicerae,Radix Scutellariae ,etc.)in Rabbit Body |
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| Zhang Zhirong,Hu Xiaoying,et al..Metabolic Kinetic Study on Baicalin of Yinhuang Granules(Flos Lonicerae,Radix Scutellariae ,etc.)in Rabbit Body[J].Chinese Traditional Patent Medicine,1996,18(6):1-3. |
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| Authors: | Zhang Zhirong Hu Xiaoying |
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| Abstract: | The blood-drug curve of baicalin in rabbit body after the single dosage of Yinhuang Granules was taken to rabbit was determined by reversed-HPLC.And the metabolic kinetic rule of baicalin in vivo was studied .As a result,the baicalin metabolism in rabbit body ac corded with pharmacokinetic model of two-room,Also the main pharmacokinetic parametersof this preparation were examined. |
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| Keywords: | Yinhuang Granules baicalin metabolic kinetics HPLC |
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