| 无花果多糖预防性给药对荷瘤小鼠的影响 |
| |
| 引用本文： | 戴伟娟,司端运,辛勤,李建美,刘善庭.无花果多糖预防性给药对荷瘤小鼠的影响[J].中成药,2001,23(10):740-742. |
| |
| 作者姓名： | 戴伟娟 司端运 辛勤 李建美 刘善庭 |
| |
| 作者单位： | 山东省济宁医学院药理教研室,山东,济南,272013 |
| |
| 基金项目： | 山东省自然科学基金资助项目(No.Y98C04033) |
| |
| 摘 要： | 目的：观察无花果多糖对荷瘤小鼠的影响。方法：以荷S180实体瘤及艾氏腹水癌（EAC）实体瘤和腹水瘤小鼠为模型，在小鼠右肢腋部皮下或腹腔内接种活瘤细胞，荷瘤前10d连续灌胃给药，观察其抑瘤率、动物存活时间及免疫器官重量的变化。结果：无花果多糖能显著抑制肿瘤的生长，对荷瘤造成的脾和胸腺指数的降低有一定恢复作用。结论：无花果多糖预防性给药对实体瘤有明显的抑制作用。
|
| 关 键 词： | 无花果多糖 荷瘤小鼠 抑瘤率 免疫器官 预防性给药 |
| 文章编号： | 1001-1528(2001)10-0740-02 |
| 修稿时间： | 2001年1月20日 |
Effect of Ficus Carica Polysaccharide on Tumor-bearing Mice |
| |
| DAI Wei juan,SI Duan yun,XIN Qin,ZHANG Wei fa,LI Jian mei,LIU Shan ting.Effect of Ficus Carica Polysaccharide on Tumor-bearing Mice[J].Chinese Traditional Patent Medicine,2001,23(10):740-742. |
| |
| Authors: | DAI Wei juan SI Duan yun XIN Qin ZHANG Wei fa LI Jian mei LIU Shan ting |
| |
| Abstract: | Objective: To observe effects of Ficus carica polysaccharide (FCPS) on tumor bearing mice. Methods: The model of S 180 bearing mice and EAC bearing mice were established, tumor cells were inoculated under the skin of right armpit or in abdominal cavity in mice after FCPS being administered orally for ten days, to calculate inhibitive rate of tumor and survial time of mice. Results: FCPS could significantly prevent the growth of tumor, there were no effects on survival time of mice.Conclusion: FCPS had a good antineoplastic effect. It is worth further study. |
| |
| Keywords: | Ficus carica polysaccharide Tumor bearing mice Tumorous inhibitory rate Immune organ |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
