| 复方灵通胶囊稳定性试验中吴茱萸碱和吴茱萸次碱的含量变化 |
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| 引用本文： | 史万忠,李世芳,刘瑾,刘力,徐德生.复方灵通胶囊稳定性试验中吴茱萸碱和吴茱萸次碱的含量变化[J].中成药,2011,33(8):1356-1360. |
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| 作者姓名： | 史万忠 李世芳 刘瑾 刘力 徐德生 |
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| 作者单位： | 上海中医药大学附属曙光医院,上海,200021 |
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| 基金项目： | 上海市科委新药基金项目(03DZ19508) |
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| 摘 要： | 目的 考察复方灵通胶囊稳定性试验中吴茱萸碱和吴茱萸次碱的含量变化.方法 建立复方灵通胶囊中吴茱萸碱和吴茱萸次碱的HPLC测定方法；分别采用加速稳定性试验和长期稳定性试验,测定加速试验条件下0、1、2、3、6个月及长期稳定性条件下0、3、6、9、12个月取样点时样品中吴茱萸碱和吴茱萸次碱的量；比较长期稳定性条件下12个月...
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| 关 键 词： | 灵通胶囊 稳定性 吴茱萸 吴茱萸碱 吴茱萸次碱 |
Content changes of evodiamine and rutaecarpine in Compound Lingtong Capsule in stability testing |
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| SHI Wan-zhong
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LI Shi-fang
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LIU Jin
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LIU Li
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XU De-sheng.Content changes of evodiamine and rutaecarpine in Compound Lingtong Capsule in stability testing[J].Chinese Traditional Patent Medicine,2011,33(8):1356-1360. |
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| Authors: | SHI Wan-zhong LI Shi-fang LIU Jin LIU Li XU De-sheng |
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| Institution: | SHI Wan-zhong,LI Shi-fang,LIU Jin,LIU Li,XU De-sheng(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China) |
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| Abstract: | AIM To study the content changes of evodiamine and rutaecarpine in Compound Lingtong Capsule in stability testing.METHODS The HPLC method of contents determination was established,and the contents were determined in the samples under the accelerated and long-term storage conditions,at time points 0,1,2,3,6 months and 0,3,6,9,12 months respectively.The ratio of peak area in its chromatogram of evodiamine to rutaecarpine from the 12 months' sample was compared with that from the 0 month's sample under the lon... |
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| Keywords: | Lingtong Capsule stability test Euodiae Fructus evodiamine rutaecarpine |
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